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Merck
CN

T2501

Sigma-Aldrich

L-甲状腺氨酸 钠盐 五水合物

synthetic (organic), ≥98% (HPLC), Thyroid hormone, powder

别名:

3-[4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基]-L-丙氨酸 钠盐, T4, 左甲状腺素钠

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关于此项目

线性分子式:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
化学文摘社编号:
分子量:
888.93
Beilstein:
5721845
EC 号:
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.32
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产品名称

L-甲状腺氨酸 钠盐 五水合物, ≥98% (HPLC), powder

生物来源

synthetic (organic)

质量水平

无菌性

non-sterile

方案

≥98% (HPLC)

表单

powder

mp

207-210 (dec.) (lit.)

溶解性

4 M NH4OH in methanol: 50 mg/mL, clear to hazy, colorless to yellow

运输

ambient

储存温度

−20°C

SMILES字符串

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

InChI key

JMHCCAYJTTWMCX-QWPJCUCISA-M

基因信息

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

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生化/生理作用

L-甲状腺素(T4) 和三碘-L-甲状腺原氨酸(T3)是由甲状腺滤泡细胞中的甲状腺球蛋白产生的含碘激素。这些激素对代谢率的刺激和对生长发育的调节似乎是由于它们对 DNA 转录和蛋白质合成的影响。

制备说明

将L-甲状腺素钠盐五水合物溶解在 4 N NH4OH 的甲醇溶液中,浓度为 50 mg/ml,产生透明至混浊、无色至黄色的溶液。

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

STOT RE 1

靶器官

Thyroid,Cardio-vascular system,Kidney

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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