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Merck
CN

T2501

L-甲状腺氨酸 钠盐 五水合物

synthetic (organic), ≥98% (HPLC), Thyroid hormone, powder

别名:

3-[4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基]-L-丙氨酸 钠盐, T4, 左甲状腺素钠

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关于此项目

线性分子式:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
化学文摘社编号:
6106-07-6
分子量:
888.93
NACRES:
NA.32
PubChem Substance ID:
24900041
UNSPSC Code:
51111800
EC Number:
200-221-4
MDL number:
MFCD00149110
Beilstein/REAXYS Number:
5721845
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥98% (HPLC)

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产品名称

L-甲状腺氨酸 钠盐 五水合物, ≥98% (HPLC), powder

InChI key

JMHCCAYJTTWMCX-QWPJCUCISA-M

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

SMILES string

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

biological source

synthetic (organic)

sterility

non-sterile

assay

≥98% (HPLC)

form

powder

mp

207-210 (dec.) (lit.)

solubility

4 M NH4OH in methanol: 50 mg/mL, clear to hazy, colorless to yellow

shipped in

ambient

storage temp.

−20°C

Quality Level

200

Gene Information

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

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相关类别

Biochem/physiol Actions

L-甲状腺素（T4） 和三碘-L-甲状腺原氨酸（T3）是由甲状腺滤泡细胞中的甲状腺球蛋白产生的含碘激素。这些激素对代谢率的刺激和对生长发育的调节似乎是由于它们对 DNA 转录和蛋白质合成的影响。

Preparation Note

将L-甲状腺素钠盐五水合物溶解在 4 N NH4OH 的甲醇溶液中，浓度为 50 mg/ml，产生透明至混浊、无色至黄色的溶液。

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H372

Hazard Classifications

STOT RE 1

target_organs

Thyroid,Cardio-vascular system,Kidney

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN3101
BCCJ6743
BCCL4029
BCCH2561
BCCG2926

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