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Merck
CN

T2830

Sigma-Aldrich

Tomatine hydrate

≥95% (HPLC)

别名:

Lycopersicin, NSC 234440, NSC 9223, Spirosolane, a-Tomatine, alpha-tomatine, b-D-galactopyranoside deriv

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关于此项目

经验公式(希尔记法):
C50H83NO21 · xH2O
化学文摘社编号:
分子量:
1034.19 (anhydrous basis)
EC 号:
UNSPSC代码:
12352200
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方案

≥95% (HPLC)

表单

powder

颜色

white to off-white

溶解性

DMSO: >20 mg/mL

储存温度

room temp

应用

Tomatine has been used as a standard for HPLC-based determination of tomatine from red and green tomatoes1. It has also been used to study its teratogenic effect using frog embryos2.

生化/生理作用

When the pure compounds were isolated, alpha-Tomatine was highly effective in inhibiting all of the cell lines, whereas dehydrotomatine, tomatidenol, and tomatidine had little, if any, effect on cell inhibition. It had been previously shown that commercial tomatine, which is customarily an approximate 10:1 mixture of α-tomatine and dehydrotomatine, strongly inhibits the growth of both colon and liver cancer cells.
It had been previously shown that commercial tomatine, which is customarily an approximate 10:1 mixture of α-tomatine and dehydrotomatine, strongly inhibits the growth of both colon and liver cancer cells.

制备说明

Tomatine hydrate is soluble in DMSO at a concentration that is greater than 20 mg/ml.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hideyuki Manabe et al.
Chemical & pharmaceutical bulletin, 59(11), 1406-1408 (2011-11-02)
In the conventional method of mixer blending extraction, the yields of the tomato-saponin, esculeoside A, in the mini and middy tomatoes were found to be 0.043% and 0.046%, respectively. In order to improve the yields, we attempted a more efficient
Yandong Shi et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 18(17), 4646-4656 (2012-06-27)
The aim of this study was to assess the activity of hedgehog signaling pathway in malignant pleural mesothelioma (MPM). The expression of hedgehog signaling components was assessed by quantitative PCR and in situ hybridization in 45 clinical samples. Primary MPM
Kyeong-Mi Choi et al.
The Journal of nutritional biochemistry, 24(1), 335-342 (2012-09-15)
Obesity is a risk factor for numerous metabolic disorders. Recently, natural compounds that may be beneficial for improving obesity have received increasing attention. In this study, we investigated whether red and green tomato extracts attenuate high-fat-diet-induced obesity in C57BL/6 mice.
Yukio Fujiwara et al.
Journal of agricultural and food chemistry, 60(10), 2472-2479 (2012-01-10)
It was previously revealed that esculeoside A, a new glycoalkaloid, and esculeogenin A, a new aglycon of esculeoside A, contained in ripe tomato ameliorate atherosclerosis in apoE-deficent mice. This study examined whether tomatidine, the aglycone of tomatine, which is a
J M Medina et al.
Parasitology, 139(10), 1253-1265 (2012-06-22)
Leishmaniasis is a set of clinically distinct infectious diseases caused by Leishmania, a genus of flagellated protozoan parasites, that affects ~12 million people worldwide, with ~2 million new infections annually. Plants are known to produce substances to defend themselves against

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