T2896
三氟丙嗪 盐酸盐
别名:
N,N-Dimethyl-2-(trifluoromethyl)-10H-phenothiazine-10-propanamine monohydrochloride
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C18H19F3N2S · HCl
化学文摘社编号:
分子量:
388.88
EC Number:
214-149-6
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
3801519
MDL number:
InChI key
FTNWXGFYRHWUKG-UHFFFAOYSA-N
InChI
1S/C18H19F3N2S.ClH/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
SMILES string
Cl.CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(F)(F)F
Gene Information
human ... DRD2(1813)
正在寻找类似产品? 访问 产品对比指南
Application
Triflupromazine hydrochloride has been used for the screening of inhibitors of S. mansoni miracidial transformation5. It has also been used to study its intracellular localization in central nervous system cells using secondary ion mass spectrometry microscopy6.
Biochem/physiol Actions
Triflupromazine is a D2 dopamine antagonist and a phenothiazine antipsychotic. It is also a potent tranquilizer7 and can significantly reduce body temperature8.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
D Jovanović-Mićić et al.
European journal of pharmacology, 272(1), 21-30 (1995-01-05)
Intracerebroventricular injection of dopamine (0.5-4.0 mg) produced dose-dependent and short-lasting emesis (1-8 min) in cats, which was abolished after ablation of the area postrema. Relatively selective alpha 2-adrenoceptor antagonists (yohimbine and idazoxan) and a mixed alpha 1- and alpha 2-adrenoceptor
L L Zhang et al.
Biology of the cell, 74(1), 99-103 (1992-01-01)
The intracellular localization of two neurotropic drugs, flunitrazepam (benzodiazepine) and triflupromazine (phenothiazine), was studied by secondary ion mass spectrometry microscopy (SIMS) in three varieties of cells. The images of the intracellular distributions of the two drugs are easily obtained by
A study of triflupromazine in dominant-lethal, cytogenetic and host-mediated assays.
V A Ray et al.
Mutation research, 18(3), 301-309 (1973-06-01)
The structure of triflupromazine, a phenothiazine 'tranquilizer' drug molecule.
Phelps, D. W., and Cordes, A. W.
Acta Crystallographica Section B, Structural Crystallography and Crystal Chemistry, 30(12), 2812-2816 (1974)
M Tatsumi et al.
European journal of pharmacology, 368(2-3), 277-283 (1999-04-08)
Using radioligand binding techniques, we determined the equilibrium dissociation constants (K(D)) for 37 neuroleptics and one metabolite of a neuroleptic (haloperidol metabolite) for the human serotonin, norepinephrine, and dopamine transporters with [3H]imipramine, [3H]nisoxetine, and [3H]WIN35428, respectively. Among neuroleptics, the four
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持