T3125
四氢叶酸
≥65% (when packaged), powder
别名:
5,6,7,8-四氢蝶酰基-
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关于此项目
经验公式（希尔记法）:
C19H23N7O6
化学文摘社编号:
分子量:
445.43
UNSPSC Code:
12352204
NACRES:
NA.51
PubChem Substance ID:
EC Number:
205-181-1
Beilstein/REAXYS Number:
9238187
MDL number:
Form:
powder
Solubility:
0.1 M phosphate pH 7.0: soluble-5 mg/mL, clear to slightly hazy, light yellow to brownish-yellow
Biological source:
synthetic
Color:
faintly yellow to light brown
biological source
synthetic
Quality Segment
form
powder
concentration
≥65% (when packaged)
color
faintly yellow to light brown
solubility
0.1 M phosphate pH 7.0: soluble-5 mg/mL, clear to slightly hazy, light yellow to brownish-yellow
storage temp.
−20°C
SMILES string
NC1=NC2=C(NC(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CN2)C(=O)N1
InChI
1S/C19H23N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,11-12,21,23H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t11?,12-/m0/s1
InChI key
MSTNYGQPCMXVAQ-KIYNQFGBSA-N
Application
四氢叶酸已用于测定四氢叶酸对多形核髓源性抑制细胞(PMN-MDSC)的抑制作用。四氢叶酸(THF)最近被用于研究核糖开关的活性。
四氢叶酸也可用作标准品，生成标准曲线用于通过高效液相色谱法(HPLC)定量分析牛奶培养物中嗜热链球菌产生的叶酸类型。它还适用于来自扭脱甲基杆菌(M. extorquens)的叶酸-四氢叶酸连接酶(MeFtfL)的酶活检测。
Biochem/physiol Actions
四氢叶酸是为氨基酸、核酸和脂质提供一碳单位的叶酸盐衍生物的母体分子。四氢叶酸盐代谢物参与嘌呤和嘧啶的合成以及氨基酸的合成和转化
Packaging
密封安瓿瓶。
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
flash_point_f
No data available
signalword
Warning
hcodes
Hazard Classifications
Self-heat. 2 - Skin Sens. 1
存储类别
4.2 - Pyrophoric and self-heating hazardous materials
flash_point_c
No data available