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文件

T3251

(±)-α-生育酚

Name: (±)-α-生育酚
Brand: SIGMA

synthetic, ≥96% (HPLC)

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别名:

DL-全-rac-α-生育酚, 维生素E

经验公式（希尔记法）:

C₂₉H₅₀O₂

CAS号:

10191-41-0

分子量:

430.71

Beilstein:

94012

EC 号:

233-466-0

MDL编号:

MFCD00006848

eCl@ss:

34058016

PubChem化学物质编号:

24900118

NACRES:

NA.77

生物来源

synthetic

质量水平

200

检测方案

≥96% (HPLC)

形式

liquid

technique(s)

HPLC: suitable

颜色

faint brown to brown
yellow to very dark yellow

溶解性

H₂O: insoluble
acetone: miscible
chloroform: miscible
ethanol: miscible
vegetable oils: miscible

密度

0.950 g/mL at 20 °C (lit.)

储存温度

2-8°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

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应用

(±)-α-生育酚已被用于制备分枝杆菌乳剂。它还用于研究其对流感病毒的免疫调节作用。

生化/生理作用

δ生育酚（维生素E）由一系列（α、β、γ和δ）手性化合物组成，这些手性化合物的不同之处在于色原烷醇环的酚部分的甲基化程度。它们起到脂溶性抗氧化剂的作用，保护细胞膜免受氧化损伤。α-生育酚被人体吸收发挥有利作用，并且它们的烟酸盐具有维生素E补充剂的作用。研究还报道，维生素E可以预防大鼠中药物诱导型癫痫引起的细胞损伤。

制备说明

(±)-α-生育酚可与氯仿、乙醇、乙醚、丙酮和植物油混溶。但是，它实际上不溶于水。 (±)-α-生育酚在碱性条件下不稳定。

象形图

GHS07

警示用语：

Warning

危险声明

H317

预防措施声明

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

危险分类

Skin Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves

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