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T3392

Testosterone 3-(O-carboxymethyl)oxime: BSA

Name: Testosterone 3-(O-carboxymethyl)oxime: BSA
Brand: SIGMA

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关于此项目

化学文摘社编号:

10190-93-9

NACRES:

NA.77

UNSPSC Code:

51111800

MDL number:

MFCD00132414

Form:

lyophilized powder

Assay:

≥98% (TLC)

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assay

≥98% (TLC)

Quality Level

200

form

lyophilized powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

extent of labeling

20-30 mol steroid per mol BSA

solubility

phosphate buffer: 1.90-2.10 mg/mL, clear to slightly hazy, colorless (pH 7.50)

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C21H31NO4/c1-20-9-7-14(22-26-12-19(24)25)11-13(20)3-4-15-16-5-6-18(23)21(16,2)10-8-17(15)20/h11,15-18,23H,3-10,12H2,1-2H3,(H,24,25)/t15-,16-,17-,18-,20-,21-/m0/s1

InChI key

VDYLVWGBLQNNAW-ZKHIMWLXSA-N

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Testosterone modulates structural synaptic plasticity of primary cultured hippocampal neurons through ERK - CREB signalling pathways.

Guoxin Guo et al.

Molecular and cellular endocrinology, 503, 110671-110671 (2019-12-06)

Although hippocampus-derived androgens play an important role in hippocampal synaptic plasticity, studies at the cellular level have received relatively less attention. Furthermore, the underlying signalling pathways associated with synaptic plasticity remain unclear. Results of the present study demonstrated that testosterone

Non-genomic mechanisms mediate androgen-induced PSD95 expression.

Yizhou Zhang et al.

Aging, 11(8), 2281-2294 (2019-04-22)

The non-genomic actions of androgen-induced synaptic plasticity have been extensively studied. However, the underlying mechanisms remain controversial. We recently found that testosterone-fetal bovine serum albumin (T-BSA), a cell membrane-impermeable complex, led to a rapid increase in the postsynaptic density 95

Detecting the presence of hippocampus membrane androgen receptors in male SAMP8 mice and their induced synaptic plasticity.

Sha Li et al.

Molecular and cellular endocrinology, 414, 82-90 (2015-07-15)

Testosterone (T), the principal androgen, and its metabolite, dihydrotestosterone (DHT), are known to mediate their effects through binding to intracellular androgen receptors (iARs). In addition to their well-known genomic effects, androgens rapidly alter neuronal excitability through a non-genomic pathway mediated

全球贸易项目编号

货号	GTIN
T3392-10MG	04061833276280

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