T3766
Thymine 1-β-D-arabinofuranoside
≥99%, powder
别名:
araT, 1-β-D-Arabinofuranosylthymine
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关于此项目
经验公式（希尔记法）:
C10H14N2O6
化学文摘社编号:
分子量:
258.23
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
210-083-7
MDL number:
Assay:
≥99%
Form:
powder
Solubility:
0.5 M HCl: 20 mg/mL, clear, colorless
Storage temp.:
2-8°C
产品名称
Thymine 1-β-D-arabinofuranoside, ≥99%
InChI key
DWRXFEITVBNRMK-UHFFFAOYSA-N
InChI
1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)
SMILES string
CC1=CN(C2OC(CO)C(O)C2O)C(=O)NC1=O
assay
≥99%
form
powder
optical activity
[α]20/D 90°, c = 5 mg/mL in water
solubility
0.5 M HCl: 20 mg/mL, clear, colorless
storage temp.
2-8°C
Quality Level
Application
1-β-D-Arabinofuranosylthymine (araT):
- maybe used as a substrate and inhibitor to study the specificity and kinetics of thymidine kinase(s), such as herpes simplex virus type 1 and 2 thymidine kinases, the HSV1-tk and, HSV2-tk gene products.
- is used to study the specificity and kinetics of various mitochondrial nucleoside kinases.
- has been used as an antiviral agent to study its efficacy on Cryptosporidium parvum in vitro.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Efficacy of select antivirals against Cryptosporidium parvum in vitro
Woods KM and Upton SJ
FEMS Microbiology Letters, 168(1), 59-63 (1998)
Kristof Y Neven et al.
Scientific reports, 10(1), 161-161 (2020-01-15)
Iodine is an essential trace element, necessary for the production of thyroid hormones, which play a key role in optimal foetal growth and (neuro-) development. To date, iodine deficiency remains a health burden in many countries. We investigated the variability
Xinyu Zheng et al.
Cancer research, 63(20), 6909-6913 (2003-10-30)
Nucleoside kinases from several species are investigated as suicide genes for treatment of malignant tumors by combined gene/chemotherapy. In the present study, we have investigated a novel strategy where nucleoside kinase proteins are directly delivered to cells without delivery of
Elisa Franzolin et al.
Biochemical and biophysical research communications, 344(1), 30-36 (2006-04-25)
Cellular models of mitochondrial thymidine kinase (TK2) deficiency require a reliable method to measure TK2 activity in whole cell extracts containing two interfering deoxyribonucleoside kinases, thymidine kinase 1 (TK1) and deoxycytidine kinase. We tested the value of the thymidine analog
Alex McAvoy et al.
PLoS computational biology, 11(8), e1004349-e1004349 (2015-08-27)
Evolutionary game theory is a powerful framework for studying evolution in populations of interacting individuals. A common assumption in evolutionary game theory is that interactions are symmetric, which means that the players are distinguished by only their strategies. In nature
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