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Merck
CN

T3824

酪氨酸酶 来源于蘑菇

lyophilized powder, ≥1000 unit/mg solid

别名:

儿茶酚氧化酶, 单酚单加氧酶, 单酚,二羟基苯丙氨酸:氧氧化还原酶, 多酚氧化酶

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
≥1000 unit/mg solid
Biological source:
fungus (mushroom)
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biological source

fungus (mushroom)

Quality Level

form

lyophilized powder

specific activity

≥1000 unit/mg solid

mol wt

119.5 kDa by electrophoresis, 128 kDa by sedimentation velocity diffusion, 133 kDa by LS

application(s)

diagnostic assay manufacturing

shipped in

wet ice

storage temp.

−20°C

General description

等电点(pI): 4.7-5
最适pH是6-7

分子量: 128 kDa通过沉降速度扩散;133kDa通过光散射测量,而119.5 kDa通过电泳。

等电点(pI): 4.7-5
最适pH是6-7

分子量: 128 kDa通过沉降速度扩散;133kDa通过光散射测量,而119.5 kDa通过电泳。

酪氨酸酶是一种含铜氧化酶,对儿茶酚和甲酚都具有活性。 它负责褐变反应。 该酶据报道有两个用于芳族底物的结合位点以及一个用于氧-铜的不同结合位点。 这里的铜很可能是Cu(I),并包括涉及将其氧化至Cu(II)离子的失活。
酪氨酸酶是一种含铜氧化酶,对儿茶酚和甲酚具有活性。 酪氨酸酶参与酪氨酸向二羟基苯丙氨酸(DOPA)的转化,而DOPA聚合则导致黑色素形成。酪氨酸酶还参与褐变反应。 据称该酶具有两个芳香族底物结合位点和一个独有的氧铜结合位点。

Application

酪氨酸酶活性在一项被开发用于治疗色素沉着过度的替代治疗剂的研究中得到了评估。 酪氨酸酶也用于研究巴基斯坦人群中的眼皮肤白化病的表型。

Biochem/physiol Actions

将酪氨酸转化成L-DOPA或酪胺转化成多巴胺

Other Notes

一个单位 = 在含有 L-酪氨酸的3 mL反应混合液中每分钟产生0.001的ΔA280,在pH 6.5,25 °C的条件下。

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

此项目有


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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货号GTIN
T3824-25KU04061835559305
T3824-500KU04061832731575
T3824-250KU04061835546404
T3824-1MU04061838174321
T3824-50KU04061835546411

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