T3830
曲西瑞宾 水合物
≥97% (HPLC)
别名:
API-2, Akt/PKB信号传导抑制剂2, NSC 154020, TCN, VD-0002, 抑制剂 V
登录查看公司和协议定价
选择尺寸
关于此项目
经验公式（希尔记法）:
C13H16N6O4 · xH2O
化学文摘社编号:
分子量:
320.30 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥97% (HPLC)
表单
powder
颜色
tan
溶解性
DMSO: >10 mg/mL
储存温度
2-8°C
SMILES字符串
O.Cn1nc(N)c2cn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c4ncnc1c24
InChI
1S/C13H16N6O4.H2O/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13;/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17);1H2/t6-,8-,9-,13-;/m1./s1
InChI key
SPGRLWCWHWRPHX-DOKXERMVSA-N
基因信息
human ... AKT1(207)
mouse ... AKT1(11651)
rat ... AKT1(24185)
相关类别
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Camilla Evangelisti et al.
Journal of cellular physiology, 226(3), 822-831 (2010-09-22)
Over the past 20 years, survival rates of T-cell acute lymphoblastic leukemia (T-ALL) patients have improved, mainly because of advances in polychemotherapy protocols. Despite these improvements, we still need novel and less toxic treatment strategies targeting aberrantly activated signaling networks
Hiroaki Kamijo et al.
The Journal of investigative dermatology, 140(3), 636-644 (2019-08-30)
Whereas atopic dermatitis (AD) is considered as a T helper 2 (Th2)-centered disease, IL-17-producing Th (Th17) cells are also activated in AD lesional skin. However, the relationship between Th17 responses and Th2 responses in AD is still to be elucidated.
Amanda Martins Baviera et al.
Molecular and cellular endocrinology, 315(1-2), 104-112 (2009-10-07)
Very little is known about the signaling pathways by which catecholamines exert anabolic effects on muscle protein metabolism, stimulating protein synthesis and suppressing proteolysis. The present work tested the hypothesis that epinephrine-induced inhibition of muscle proteolysis is mediated through the
A Griveau et al.
Oncogene, 35(38), 5033-5042 (2016-04-05)
Little is known about the biological role of the phospholipase A2 receptor (PLA2R1) transmembrane protein. In recent years, PLA2R1 has been shown to have an important role in regulating tumor-suppressive responses via JAK2 activation, but the underlying mechanisms are largely
Tsubasa Furuhashi et al.
Physiology & behavior, 168, 20-23 (2016-11-05)
Autonomic nervous system (ANS) imbalances are involved in the etiology of cancer, allergy, and collagen diseases. Previously, we hypothesized that FoxO and HSF-1 limit autonomic stress responses via negative feedback on the ANS. Here, we evaluated the role of AKT
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持