T3830
曲西瑞宾 水合物
≥97% (HPLC)
别名:
API-2, Akt/PKB信号传导抑制剂2, NSC 154020, TCN, VD-0002, 抑制剂 V
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关于此项目
经验公式（希尔记法）:
C13H16N6O4 · xH2O
化学文摘社编号:
分子量:
320.30 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥97% (HPLC)
表单
powder
颜色
tan
溶解性
DMSO: >10 mg/mL
储存温度
2-8°C
SMILES字符串
O.Cn1nc(N)c2cn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c4ncnc1c24
InChI
1S/C13H16N6O4.H2O/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13;/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17);1H2/t6-,8-,9-,13-;/m1./s1
InChI key
SPGRLWCWHWRPHX-DOKXERMVSA-N
基因信息
human ... AKT1(207)
mouse ... AKT1(11651)
rat ... AKT1(24185)
相关类别
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Tsubasa Furuhashi et al.
Physiology & behavior, 168, 20-23 (2016-11-05)
Autonomic nervous system (ANS) imbalances are involved in the etiology of cancer, allergy, and collagen diseases. Previously, we hypothesized that FoxO and HSF-1 limit autonomic stress responses via negative feedback on the ANS. Here, we evaluated the role of AKT
Muhammad Miftahussurur et al.
PloS one, 11(12), e0166199-e0166199 (2016-12-03)
Information regarding Helicobacter pylori antibiotic resistance in Indonesia was previously inadequate. We assessed antibiotic susceptibility for H. pylori in Indonesia, and determined the association between virulence genes or genetic mutations and antibiotic resistance. We recruited 849 dyspeptic patients who underwent
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The Journal of investigative dermatology, 140(3), 636-644 (2019-08-30)
Whereas atopic dermatitis (AD) is considered as a T helper 2 (Th2)-centered disease, IL-17-producing Th (Th17) cells are also activated in AD lesional skin. However, the relationship between Th17 responses and Th2 responses in AD is still to be elucidated.
Rocío López de la Lama et al.
PloS one, 13(8), e0202971-e0202971 (2018-08-30)
Misconceptions, lack of knowledge, and negative attitudes towards sharks act as barriers preventing actions required to tackle threats to shark populations, limiting the success of global shark conservation initiatives. Peru, a major player for the international trade of shark products
Camilla Evangelisti et al.
Journal of cellular physiology, 226(3), 822-831 (2010-09-22)
Over the past 20 years, survival rates of T-cell acute lymphoblastic leukemia (T-ALL) patients have improved, mainly because of advances in polychemotherapy protocols. Despite these improvements, we still need novel and less toxic treatment strategies targeting aberrantly activated signaling networks
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