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Merck
CN

T4512

(±)-紫杉叶素 水合物

≥90% (HPLC)

别名:

3,3′,4′,5,7-五羟基黄酮 水合物, 二氢槲皮素 水合物

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关于此项目

经验公式（希尔记法）:
C15H12O7 · xH2O
化学文摘社编号:
24198-97-8
分子量:
304.25 (anhydrous basis)
NACRES:
NA.25
PubChem Substance ID:
24278739
UNSPSC Code:
12352200
MDL number:
MFCD11044454

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InChI

1S/C15H12O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,14-19,21H;1H2/t14-,15+;/m0./s1

SMILES string

O.O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3

InChI key

DNQPGSVMBPSRIR-LDXVYITESA-N

assay

≥90% (HPLC)

form

powder

solubility

DMSO: 20 mg/mL

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... Hexa(15211)

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相关类别

General description

花旗松素(Taxifolin)或二氢槲皮素(dihydroquercetin)是天然产生的次级代谢物，存在于洋葱、奶蓟、花旗松树皮、法国海岸松树皮等多种植物中。

Application

(±)-花旗松素已用于评估其协同海藻糖对解冻后公羊精液的质量改善效果。它可用作高效液相色谱法(HPLC)的参考标准品，分析鬼罂粟P. orientale(POE)乙醇提取物的生物活性成分。

Biochem/physiol Actions

(±)-花旗松素具有抗炎、抗癌、抗病毒和抗微生物等多种药理活性。它具有神经保护和肝保护作用，也具有抗心血管疾病的保护作用。
类黄酮，抗氧化剂。通过靶向脂肪酸合酶活性来抑制癌细胞中的脂肪生成。

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000402339
0000402339
0000238240
0000238240
0000159553

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Yung-Jia Chiu et al.
Journal of food and drug analysis, 26(1), 369-379 (2018-02-02)
Polygonum orientale L. (Polygonaceae) fruits have various medicinal uses, but their hepatoprotective effects have not yet been studied. This study investigated the hepatoprotective activity of the ethanolic extract of P. orientale (POE) fruits against carbon tetrachloride (CCl4)-induced acute liver injury
Christudas Sunil et al.
Phytochemistry, 166, 112066-112066 (2019-07-22)
Taxifolin (3,5,7,3,4-pentahydroxy flavanone or dihydroquercetin) is a flavonoid commonly found in onion, milk thistle, French maritime pine bark and Douglas fir bark. It is also used in various commercial preparations like Legalon™, Pycnogenol®, and Venoruton®. This review focuses on taxifolin's
Cong Cai et al.
Frontiers in pharmacology, 9, 1286-1286 (2018-11-30)
Osteoporosis is a highly prevalent disease which has been a major public health problem and considered to be associated with chronic low-grade systemic inflammation and oxidative damage. Taxifolin is a natural flavonoid and possesses many pharmacological activities including antioxidant and
Mustafa Numan Bucak et al.
Cryobiology, 96, 19-29 (2020-09-06)
This study aimed to evaluate the comparative effects of taxifolin hydrate and trehalose on the quality of frozen-thawed ram spermatozoa for the first time. Ejaculates collected from six mature rams were pooled, and divided to eight equal aliquots to extend

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膳食抗氧化剂

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。

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