T4626
Nα-p甲苯磺酰基-L-精氨酸甲酯 盐酸盐
≥98% (TLC), suitable for ligand binding assays
别名:
TAME 盐酸盐
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线性分子式:
H2NC(=NH)NH(CH2)3CH(NHSO2C6H4CH3)CO2CH3 · HCl
化学文摘社编号:
分子量:
378.87
Beilstein:
3922357
EC 号:
MDL编号:
UNSPSC代码:
12352103
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
产品名称
Nα-p甲苯磺酰基-L-精氨酸甲酯 盐酸盐,
方案
≥98% (TLC)
表单
powder
技术
ligand binding assay: suitable
颜色
white
mp
145-147 (lit.)
储存温度
−20°C
SMILES字符串
Cl.COC(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1ccc(C)cc1
InChI
1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1
InChI key
JIQFFACVQXXHMY-YDALLXLXSA-N
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相关类别
一般描述
胰蛋白酶、凝血酶、纤溶酶和其他蛋白酶的底物。
应用
Nα-对甲苯磺酰基-L-精氨酸甲酯盐酸盐已被用作酯水解底物，用于评估中肠提取物中胰蛋白酶样活性。它也已被用作测定胰酶和人肠样品中胰蛋白酶活性的底物。
生化/生理作用
Nα-对甲苯磺酰基-L-精氨酸甲酯（TAME）与后期促进复合物（APC）结合并阻止其被Cdc20和Cdh1激活。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Sappasith Klomklao et al.
Journal of agricultural and food chemistry, 54(15), 5617-5622 (2006-07-20)
Trypsin from tongol tuna (Thunnus tonggol) spleen was purified to 402-fold by ammonium sulfate precipitation, followed by a series of chromatographic separations. The molecular mass of trypsin was estimated to be 24 kDa by size-exclusion chromatography and sodium dodecyl sulfate-polyacrylamide
Character of a wheat amylase inhibitor preparation and effects on fasting human pancreaticobiliary secretions and hormones
Choudhury A, et al.
Gastroenterology, 111(5), 1313-1320 (1996)
In vitro digestibility of goat milk and kefir with a new standardised static digestion method (INFOGEST cost action) and bioactivities of the resultant peptides
El SN, et al.
Food & Function, 6(7), 2322-2330 (2015)
Xing Zeng et al.
Cancer cell, 18(4), 382-395 (2010-10-19)
Microtubule inhibitors are important cancer drugs that induce mitotic arrest by activating the spindle assembly checkpoint (SAC), which, in turn, inhibits the ubiquitin ligase activity of the anaphase-promoting complex (APC). Here, we report a small molecule, tosyl-L-arginine methyl ester (TAME)
A modified spectrophotometric determination of chymotrypsin, trypsin, and thrombin.
B C HUMMEL
Canadian journal of biochemistry and physiology, 37, 1393-1399 (1959-12-01)
相关内容
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