T5067
Anti-TRPC3 antibody produced in rabbit
affinity isolated antibody, lyophilized powder
别名:
Anti-Transient receptor potential cation channel, subfamily C, member 3
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
rat
Citations:
11
Technique(s):
western blot: suitable
Uniprot accession no.:
产品名称
Anti-TRPC3 antibody produced in rabbit, affinity isolated antibody, lyophilized powder
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
rat
concentration
≥0.6 mg/mL (after reconstitution)
technique(s)
western blot: suitable
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Trpc3(22065)
rat ... Trpc3(60395)
Biochem/physiol Actions
TRPC3 (transient receptor potential-canonical 3) participates in motility and capacitation of sperm. It is responsible for the proliferation of ovarian cancer cell in vitro and in vivo. TRPC3 plays a key role in a wide spectrum of Ca2+ signaling mechanisms. Elevated expression of TRPC3 has been observed in spontaneously hypertensive rats (SHR).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Transient receptor potential-canonical 3 (TRPC3) is a member of TRP superfamily. It is mainly expressed in brain. The TRPC3 gene is mapped to human chromosome 4.
Immunogen
peptide corresponding to amino acid residues 822-835 of mouse TRPC3.
Physical form
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Activation of a TRPC3-Dependent Cation Current through the Neurotrophin BDNF
Li HS
Neuron, 24, 261-273 (1999)
Follicle-stimulating hormone enhances the proliferation of ovarian cancer cells by activating transient receptor potential channel C3
Tao X
Endocrine-Related Cancer, 20, 415-429 (2013)
Increased Transient Receptor Potential Channel TRPC3 Expression in Spontaneously Hypertensive Rats
Liu D
American Journal of Hypertension, 18, 1503-1507 (2005)
Genotype of an individual single nucleotide polymorphism regulates DNA methylation at the TRPC3 alternative promoter.
Martin-Trujillo A
Epigenetics, 6, 1236-1241 (2011)
Hideki Hino et al.
Anesthesiology, 133(5), 1077-1092 (2020-09-12)
Local anesthetics, particularly potent long acting ones such as bupivacaine, can cause cardiotoxicity by inhibiting sodium ion channels; however, the impact of left ventricular hypertrophy on the cardiotoxicity and the underlying mechanisms remain undetermined. Transient receptor potential canonical (TRPC) channels
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