T5568
Tyrphostin AG 835
≥92%
别名:
(+)-(S)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide, Tyrphostin B50
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关于此项目
经验公式（希尔记法）:
C18H16N2O3
化学文摘社编号:
分子量:
308.33
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥92%
form
crystalline
potency
IC50 (860 nanomolar for the inhibition of EGFR-kinase activity.)
solubility
DMSO or ethanol: soluble
storage temp.
−20°C
SMILES string
C[C@H](NC(=O)\C(=C\c1ccc(O)c(O)c1)C#N)c2ccccc2
InChI
1S/C18H16N2O3/c1-12(14-5-3-2-4-6-14)20-18(23)15(11-19)9-13-7-8-16(21)17(22)10-13/h2-10,12,21-22H,1H3,(H,20,23)/b15-9+/t12-/m0/s1
InChI key
UMGQVUWXNOJOSJ-DGGAMASNSA-N
Gene Information
human ... MST1R(4486), PTK2(5747), PTK6(5753), PTK7(5754), TWF1(5756), TXK(7294)
Biochem/physiol Actions
Protein tyrosine kinase inhibitor.
Preparation Note
Tyrphostin AG 835 is soluble in ethanol and DMSO.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)