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T5639

替卡西林二钠盐

Name: 替卡西林 二钠盐
Brand: SIGMA

别名:

(2S,5R,6R)-6-[[(2R)-Carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid disodium salt

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关于此项目

经验公式（希尔记法）:

C₁₅H₁₄N₂Na₂O₆S₂

化学文摘社编号:

4697-14-7

分子量:

428.39

NACRES:

NA.85

PubChem Substance ID:

24900306

UNSPSC Code:

51282427

MDL number:

MFCD07787410

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属性

biological source

semisynthetic

Quality Segment

200

form

powder or crystals

color

white to light yellow

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](C([O-])=O)c3ccsc3)C(=O)N2[C@H]1C([O-])=O

InChI

1S/C15H16N2O6S2.2Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);;/q;2*+1/p-2/t7-,8-,9+,12-;;/m1../s1

InChI key

ZBBCUBMBMZNEME-QBGWIPKPSA-L

说明

General description

Chemical structure: β-lactam

Application

Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It is commonly used in combination with clavulanate in order to improve it′s efficacy. It is used to study appropriate dosing in pediatric patients who have cystic fibrosis.

Biochem/physiol Actions

Ticarcillin is a β-Lactam antibiotic that prevents bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking by inhibiting peptidoglycan transpeptidases. It is derived from penicillin and is similar to carbenicillin in action. Ticarcillin is susceptible to degradation by β-lactamases.

Packaging

Preparation Note

Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep in a dry place.

Other Notes

β-Lactam antibiotic

Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep in a dry place.

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H315,H319,H334,H335

pcodes

P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c