assay
≥98.00% (TLC)
Quality Segment
form
powder
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
extent of labeling
~3 mol FITC per mol BSA, ~10 mol steroid per mol BSA
technique(s)
flow cytometry: suitable
solubility
water: 1.90-2.10 mg/mL, clear to faintly hazy, orange
shipped in
ambient
storage temp.
2-8°C
Application
Testosterone 3-(O-carboxymethyl)oxime: BSA-FITC has been used for flow cytometric assays in serum-free cell cultures2. It has also been used for fluorescence labeling experiments in L6 cells3.
Biochem/physiol Actions
Studies have reported that BSA-coupled testosterone can block the growth of LNCaP cells. Furthermore, it can activate Fas protein and cell death, as well as reduce the translocation, adhesion and incursion of iAR-negative, DU145 prostate cancer cells2.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges