T6060
Thioperamide 马来酸盐
别名:
MR-12842, N-Cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioamide 马来酸盐
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关于此项目
经验公式（希尔记法）:
C15H24N4S · C4H4O4
化学文摘社编号:
分子量:
408.52
UNSPSC Code:
12352200
MDL number:
solubility
H2O: soluble 10 mg/mL, DMSO: soluble 12 mg/mL, ethanol: soluble 3 mg/mL
SMILES string
OC(=O)\C=C/C(O)=O.S=C(CC1CCCCC1)N2CCC(CC2)c3c[nH]cn3
InChI
1S/C16H25N3S.C4H4O4/c20-16(10-13-4-2-1-3-5-13)19-8-6-14(7-9-19)15-11-17-12-18-15;5-3(6)1-2-4(7)8/h11-14H,1-10H2,(H,17,18);1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
REZRBLGMJZZSID-BTJKTKAUSA-N
Application
Thioperamide maleate has been used to study its effect on tau and TDP-43 aggregation3. It has also been used to study its effects on histamine induced contraction of trachealis in horses4.
Biochem/physiol Actions
Thioperamide is a H3 histamine receptor antagonist. Studies have reported that it can enhance MK-801-induced behavioral changes in rats5.
Preparation Note
Thioperamide maleate is soluble in water at 10 mg/ml, in ethanol at 3 mg/ml and in DMSO at 12 mg/ml.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves