T6069
三乙烯硫代磷酰胺
别名:
N,N′,N″-三乙撑硫代磷酰胺, 三(1-吖丙啶基)硫代磷酰, 三亚乙基硫代磷酰胺, 三胺硫磷, 噻替哌, 噻替派, 塞替派, 硫次膦基三氮丙啶
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关于此项目
经验公式（希尔记法）:
C6H12N3PS
化学文摘社编号:
分子量:
189.22
EC 号:
MDL编号:
UNSPSC代码:
51102829
PubChem化学物质编号:
NACRES:
NA.85
表单
solid
储存条件
(Keep container tightly closed in a dry and well-ventilated place.)
颜色
white
抗生素抗菌谱
neoplastics
作用机制
DNA synthesis | interferes
储存温度
2-8°C
SMILES字符串
S=P(N1CC1)(N2CC2)N3CC3
InChI
1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2
InChI key
FOCVUCIESVLUNU-UHFFFAOYSA-N
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一般描述
化学结构：氮丙啶
应用
多官能烷基化剂
生化/生理作用
该不稳定的氮碳基团会与 DNA 烷基化，从而导致不可逆的 DNA 损伤。它们通过使 DNA 双螺旋链中的鸟嘌呤核苷交联来阻止肿瘤生长、直接攻击 DNA。DNA 链无法解开和分离，从而阻止了细胞分裂。
分析说明
溶解度 - 完全溶于水、氯仿和乙醇（96%）
其他说明
保存于密闭容器内，置于干燥通风处。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 2 Oral - Carc. 1B
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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