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T6260

牛磺鹅去氧胆酸钠

别名:

2-（[3α,7α-二羟基-24-氧代-5β-胆烷-24-基] 氨基）乙磺酸 钠盐, 3α,7α-二羟基-5β-胆烷-24-酸 N-（2-磺乙基）酰胺 钠盐, 牛磺鹅脱氧胆酸 钠盐

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关于此项目

经验公式（希尔记法）:
C26H44NNaO6S
化学文摘社编号:
6009-98-9
分子量:
521.69
UNSPSC Code:
41141802
NACRES:
NA.25
PubChem Substance ID:
24900362
MDL number:
MFCD00036745
Beilstein/REAXYS Number:
3901205
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description

anionic

Quality Level

200

assay

≥95.0% (TLC)

form

powder

mol wt

521.69 g/mol

CMC

4

HLB

20.1

functional group

sulfonic acid

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(NCCS(=O)([O-])=O)=O.[Na+]

InChI

1S/C26H45NO6S.Na/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29;/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17+,18-,19-,20+,21+,22-,24?,25+,26-;/m1./s1

InChI key

IYPNVUSIMGAJFC-ULWOGUKGSA-M

相关类别

General description

一种离子洗涤剂，用于溶解脂肪和蛋白质。
牛磺鹅去氧胆酸钠是一种胆汁酸，可用作阴离子洗涤剂。

Application

牛磺鹅去氧胆酸钠已用于一项研究，以评估胰岛 β-细胞有助于 BA 依赖的葡萄糖调节。 也被用于研究胆汁酸盐 在体内对牛磺胆酸钠共转运多肽 (Ntcp) 的短期反馈调节 。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000547590
0000547587
0000547591
0000519370
0000547590

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B I Cohen et al.
Journal of lipid research, 18(2), 223-231 (1977-03-01)
Sterol metabolism studies using a combination of isotopic and chromatographic procedures were carried out in rats fed either a low-cholesterol stock diet or a stock diet containing 0.1% cholesterol. The primary bile acids, sodium taurochenodeoxycholate and sodium taurocholate, were added
Kalaimathi Govindarajan et al.
PloS one, 11(12), e0167319-e0167319 (2016-12-03)
Disruptions to circadian rhythm in mice and humans have been associated with an increased risk of obesity and metabolic syndrome. The gut microbiota is known to be essential for the maintenance of circadian rhythm in the host suggesting a role
T M Zaved Waise et al.
Molecular metabolism, 44, 101132-101132 (2020-12-03)
The mechanism of nutrient sensing in the upper small intestine (USI) and ileum that regulates glucose homeostasis remains elusive. Short-term high-fat (HF) feeding increases taurochenodeoxycholic acid (TCDCA; an agonist of farnesoid X receptor (FXR)) in the USI and ileum of
Colin N Young et al.
The Journal of clinical investigation, 122(11), 3960-3964 (2012-10-16)
Although endoplasmic reticulum (ER) stress is a pathologic mechanism in a variety of chronic diseases, it is unclear what role it plays in chronic hypertension (HTN). Dysregulation of brain mechanisms controlling arterial pressure is strongly implicated in HTN, particularly in
M B Jiménez-Castro et al.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 12(12), 3257-3271 (2012-09-22)
Numerous steatotic livers are discarded for transplantation because of their poor tolerance to ischemia-reperfusion (I/R). We examined whether tauroursodeoxycholic acid (TUDCA), a known inhibitor of endoplasmic reticulum (ER) stress, protects steatotic and nonsteatotic liver grafts preserved during 6 h in
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全球贸易项目编号

货号GTIN
T6260-250MG04061833613948
T6260-1G04061826759165
T6260-100MG04061837358531

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