T6576
L -茶氨酸
别名:
Nγ-乙基-L-谷氨酰胺, L-谷氨酸γ-(乙酰胺), Suntheanine茶氨酸
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关于此项目
经验公式（希尔记法）:
C7H14N2O3
化学文摘社编号:
分子量:
174.20
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
221-379-0
MDL number:
InChI key
DATAGRPVKZEWHA-YFKPBYRVSA-N
InChI
1S/C7H14N2O3/c1-2-9-6(10)4-3-5(8)7(11)12/h5H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
SMILES string
CCNC(=O)CC[C@H](N)C(O)=O
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Biochem/physiol Actions
茶氨酸能够与大鼠皮层神经元的 AMPA、钾盐镁矾和 NMDA 甘氨酸受体结合但亲和力低于谷氨酸。已对其作为谷氨酸盐转运抑制剂进行了研究，防止荷 M5076 卵巢肉瘤小鼠细胞摄取谷氨酸盐，并增加多柔比星对 M5076 小鼠肿瘤生长的影响。
Other Notes
茶氨酸是一种谷氨酰胺的氨基酸类似物，存在于绿茶中。
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
Kim Zarse et al.
European journal of nutrition, 51(6), 765-768 (2012-03-17)
Compounds that delay aging in model organisms may be of significant interest to anti-aging medicine, since these substances potentially provide pharmaceutical approaches to promote healthy lifespan in humans. We here aimed to test whether pharmaceutical concentrations of L-theanine, a putative
Jamila H Siamwala et al.
The Journal of nutritional biochemistry, 24(3), 595-605 (2012-07-24)
Consumption of tea (Camellia sinensis) improves vascular function and is linked to lowering the risk of cardiovascular disease. Endothelial nitric oxide is the key regulator of vascular functions in endothelium. In this study, we establish that l-theanine, a non-protein amino-acid
J Song et al.
The journal of nutrition, health & aging, 16(1), 31-34 (2012-01-13)
This review summarizes the literature on the association between tea consumption and cognitive health in late life. Population-based studies reviewed in this article suggest that tea drinking has beneficial effects on cognitive function of elderly persons. However, a cause-effect relationship
Hwan-Soo Jang et al.
Pharmacology, biochemistry, and behavior, 101(2), 217-221 (2012-01-31)
L-theanine has been reported to inhibit the excitatory effects of caffeine. The present study examined the effects of L-theanine on caffeine-induced sleep disturbances in rats. Rats received the following drug pairings: saline and saline (Control), 7.5 mg/kg caffeine and saline
Sabry Attia
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(5), 1749-1754 (2012-03-15)
The possible chemoprotective activity of theanine against irinotecan-induced genomic DNA damage towards mouse bone marrow cells was investigated. Chromosomal aberrations, DNA damage, micronuclei formation and mitotic activity were studied in the current study as markers of genomic damage. Oxidative DNA
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