T6632
胸苷磷酸化酶，重组 来源于大肠杆菌
recombinant, expressed in E. coli, buffered aqueous solution, ≥900 units/mL, 0.2 μm filtered
别名:
胸苷：正磷酸脱氧-D-核糖基转移酶
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Recombinant:
expressed in E. coli
Concentration:
≥900 units/mL
recombinant
expressed in E. coli
Quality Segment
sterility
0.2 μm filtered
form
buffered aqueous solution
concentration
≥900 units/mL
UniProt accession no.
storage temp.
2-8°C
Gene Information
Escherichia coli K12 ... deoA(948901)
General description
Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation.
Application
Thymidine phosphorylase has been used in a study to evaluate biomarkers for advanced breast cancer patients treated with capecitabine-based first-line chemotherapy. Thymidine phosphorylase has also been used in a study to investigate implications for the clinical efficacy of nucleoside analogues.
Biochem/physiol Actions
一种对胸腺嘧啶可逆性转化为胸腺嘧啶进行催化的酶。 胸苷磷酸化酶是嘧啶核苷挽救途径的一部分。
一种对胸腺嘧啶可逆性转化为胸腺嘧啶进行催化的酶。胸苷磷酸化酶是嘧啶核苷挽救途径的一部分。该途径允许嘧啶碱基被回收用于核苷酸生物合成，而1-磷酸戊糖被转化为磷酸戊糖分流和糖酵解的中间体。 大肠埃希菌胸苷磷酸化酶与人序列具有40%的序列同源性，已发现该序列与血管生成剂血小板衍生的内皮生长因子相同。 在鸡绒膜尿囊膜测定中，纯化的大肠埃希菌酶已显示出刺激血管生长的作用。
Physical form
Solution in 0.5 M potassium phosphate containing 2 mM uracil, 0.02% sodium azide and bovine serum albumin
Preparation Note
Cloned from E. coli and produced in overexpressing E. coli
Other Notes
One unit will convert 1.0 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per min at pH 7.4 at 25°C.
Still not finding the right product?
Explore all of our products under 胸苷磷酸化酶，重组 来源于大肠杆菌
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)