T7189
Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human
>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
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关于此项目
Form:
lyophilized powder
Assay:
>95% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in NSO cells
Mol wt:
52.6 kDa
biological source
human
Quality Segment
recombinant
expressed in NSO cells
assay
>95% (SDS-PAGE)
form
lyophilized powder
potency
0.004-0.016 mg per mL ED50
mol wt
52.6 kDa
packaging
pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... TNFRSF1B(7133)
Application
Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human can be used as a test compound for analyzing the interaction between tumor necrosis factor (TNF) and its two soluble receptors by using surface plasmon resonance (SPR) technique.
Biochem/physiol Actions
Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human belongs to TNF family of receptors and mediates the metabolic effects of TNF-α. Tumor Necrosis Factor Soluble Receptor II blocks the TNF-α-induced apoptosis and hence regulates the TNF-α function. It also has a pivotal role in neutralizing the biological activities of both TNF-α and TNF-β.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline
Analysis Note
The biological activity is measured by its ability to neutralize the TNF-α mediated cytotoxicity in mouse L-929 cells in the presence of the metabolic inhibitor actinomycin D.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T7189-50UG | 04061837372377 |