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Merck
CN

T7515

Sigma-Aldrich

牛磺石胆酸钠

别名:

3α-羟基-5β-胆烷-24-羧酸-N-（2-磺乙基）酰胺, 牛磺石胆酸 钠盐

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关于此项目

线性分子式:
C26H44NO5SNa
化学文摘社编号:
6042-32-6
分子量:
505.69
UNSPSC代码:
12161900
PubChem化学物质编号:
24900457
NACRES:
NA.25

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描述

anionic

方案

≥97.0% (TLC)

分子量

505.69 g/mol

应用

detection

SMILES字符串

C[C@H](CCC(NCCS(=O)(O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C.[Na]

InChI

1S/C26H45NO5S.Na.H/c1-17(4-9-24(29)27-14-15-33(30,31)32)21-7-8-22-20-6-5-18-16-19(28)10-12-25(18,2)23(20)11-13-26(21,22)3;;/h17-23,28H,4-16H2,1-3H3,(H,27,29)(H,30,31,32);;/t17-,18-,19-,20+,21-,22+,23+,25+,26-;;/m1../s1

InChI key

CMXYYIRKQPXCIE-RLHFEMFKSA-N

相关类别

一般描述

牛磺胆酸钠是一种具有洗涤剂特性的胆汁盐，该特性使其能够溶解不溶性脂质。

应用

牛磺胆酸钠已被用于评估石油烃残留物的胃肠道吸附的控制因素。 它还被用于研究诱导胆汁淤积的大鼠中Na+、K+-腺苷三磷酸酶（Na+、K+-ATP酶）活性的降低。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000373029
0000334511
0000310778
0000334511
0000310778

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Solubility of bile salts.
D M Small et al.
Nature, 221(5177), 265-267 (1969-01-18)
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NorUDCA (24-norursodeoxycholic acid), the C₂₃-homolog of ursodeoxycholic acid (UDCA), showed remarkable therapeutic effects in cholestatic Mdr2 (Abcb4) (multidrug resistance protein 2/ATP-binding cassette b4) knockout mice with sclerosing/fibrosing cholangitis. In contrast to UDCA, norUDCA is inefficiently conjugated in human and rodent
David M Booth et al.
Gastroenterology, 140(7), 2116-2125 (2011-03-01)
Oxidative stress is implicated in the pathogenesis of pancreatitis, but clinical trials of antioxidants have produced conflicting results. We examined the role of intracellular reactive oxygen species (ROS) in pancreatic acinar cell injury. Freshly isolated murine and human pancreatic acinar
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实验方案

HPLC Separation of Bile Acids with Ascentis Express C18

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