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Merck
CN

T7697

Sigma-Aldrich

I-OMe-Tyrphostin AG 538

solid

别名:

α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone, I-OMe-AG 538

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About This Item

经验公式(希尔记法):
C17H12INO5
CAS Number:
分子量:
437.19
MDL编号:
UNSPSC代码:
12352203
PubChem化学物质编号:
NACRES:
NA.77

表单

solid

质量水平

溶解性

DMSO: 50 mg/mL

储存温度

−20°C

SMILES字符串

COc1cc(cc(I)c1O)\C=C(/C#N)C(=O)c2ccc(O)c(O)c2

InChI

1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+

InChI key

HSRMHXWCTRFVHK-NYYWCZLTSA-N

基因信息

应用

I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors.

生化/生理作用

Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor.

特点和优势

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

制备说明

I-OMe-Tyrphostin AG 538 is soluble in DMSO at 50 mg/ml.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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