T8024
河鲀毒素
≥98% (HPLC), powder
别名:
Fugu poison, Maculotoxin, TTX, Tarichatoxin
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经验公式（希尔记法）:
C11H17N3O8
化学文摘社编号:
分子量:
319.27
EC Number:
224-458-8
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
49176
MDL number:
assay
≥98% (HPLC)
form
powder
color
white
solubility
dilute citrate or acetate buffer: 1 mg/mL (dissolve at pH 4-5. Aqueous solutions, pH 4-5, are stable if stored frozen.), strong acid or alkaline solutions: unstable (destroyed by boiling at pH 2.)
storage temp.
2-8°C
SMILES string
[H][C@]12OC3(O)OC(C4[C@@H](O)NC(=N)NC4([C@@H]1O)[C@@H]3O)[C@@]2(O)CO
InChI
1S/C11H17N3O8/c12-8-13-6(17)2-4-9(19,1-15)5-3(16)10(2,14-8)7(18)11(20,21-4)22-5/h2-7,15-20H,1H2,(H3,12,13,14)/t2?,3-,4?,5+,6-,7+,9+,10?,11?/m1/s1
InChI key
CFMYXEVWODSLAX-IXUBDLNJSA-N
Gene Information
rat ... Scnn1g(24768)
Application
Biochem/physiol Actions
Reversible, selective blocker of Na+ channels.
Reversible, selective blocker of Na+ channels; blocks propagation of impulses in excitable membranes. Used to characterize sodium channels in excitable membranes and to study the role of sodium channels in normal physiology and disease.
Preparation Note
Tetrodotoxin is soluble in dilute citrate or acetate buffer at 1 mg/ml (pH 4-5). Aqueous solutions are stable at pH 4-5 if stored frozen. However, tetrodotoxin is unstable in strong acid or alkaline solutions and is destroyed by boiling at pH2.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Oral
存储类别
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges