T8390
睾酮 3-(O-羧甲基)肟
别名:
17β-羟基-4-胆甾烯-3-酮 3-(O-羧甲基)肟, 4-胆甾烯-17β-醇-3-酮3-(O-羧甲基)肟
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关于此项目
经验公式（希尔记法）:
C21H31NO4
化学文摘社编号:
分子量:
361.48
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
sterility
non-sterile
Quality Level
assay
≥98.00% (TLC)
form
powder
drug control
Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
solubility
ethanol: soluble 49-51 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
room temp
SMILES string
[H][C@@]12CCC3=CC(\CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@@H](O)CC[C@@]24[H])=N\OCC(O)=O
InChI
1S/C21H31NO4/c1-20-9-7-14(22-26-12-19(24)25)11-13(20)3-4-15-16-5-6-18(23)21(16,2)10-8-17(15)20/h11,15-18,23H,3-10,12H2,1-2H3,(H,24,25)/b22-14+/t15-,16-,17-,18-,20-,21-/m0/s1
InChI key
VDYLVWGBLQNNAW-UVTKPVMCSA-N
Application
睾酮3-（O-羧甲基）肟已用于制备辣根过氧化物酶（HRP）标记的睾酮，以通过酶免疫测定法测量血浆睾酮浓度。
睾酮3-（O-羧甲基）肟已用于电鱼Apteronotus中性二态性的激素分析。该睾酮衍生物也已用于开发用于检测水样中睾酮的环境生物传感器。
Biochem/physiol Actions
雄激素指导男性生殖系统和第二性征的发育。睾酮是由睾丸分泌的雄激素。该激素在靶组织中被5α还原酶转化为二氢睾酮（DHT）。DHT和睾酮都需要雄激素受体（一种配体依赖性核转录因子）来介导其生物学功能。
雄激素在胚胎发生和青春期指导雄性表型的发展。睾酮是由睾丸分泌的雄激素。该激素在靶组织中转化为二氢睾酮，在那里它可以介导几种生物学功能。
Preparation Note
睾酮3-（O-羧甲基）肟可溶于乙醇，浓度为49-51 mg/ml，并产生一种透明无色至淡黄色的溶液。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T8390-100MG | 04061832856889 |