T8951
桔皮素
≥95% (HPLC)
别名:
4′,5,6,7,8-五甲氧基黄酮, 5,6,7,8-四甲基-2-(4-甲氧基苯基)-4H-1-苯并吡喃-4-酮, NSC 53909, NSC 618905, 桔皮素
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关于此项目
经验公式（希尔记法）:
C20H20O7
化学文摘社编号:
分子量:
372.37
Beilstein:
351695
EC 号:
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25
质量水平
方案
≥95% (HPLC)
应用
metabolomics
vitamins, nutraceuticals, and natural products
SMILES字符串
COc1ccc(cc1)C2=CC(=O)c3c(OC)c(OC)c(OC)c(OC)c3O2
InChI
1S/C20H20O7/c1-22-12-8-6-11(7-9-12)14-10-13(21)15-16(23-2)18(24-3)20(26-5)19(25-4)17(15)27-14/h6-10H,1-5H3
InChI key
ULSUXBXHSYSGDT-UHFFFAOYSA-N
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一般描述
桔皮素是一种多甲氧基黄酮，主要从柑橘类水果的果皮中提取，如 甜橙 和 中国桔子。
应用
桔皮素已被用作抗氧化剂和抗真菌剂，用于测试其对 稻瘟病原菌的铁死亡抑制、分生孢子发育和附着胞形成的影响。它还被用作辅助化疗剂，以研究其与5-氟尿嘧啶(5-Fu)联合使用对WiDr结肠癌细胞的细胞毒性作用。
生化/生理作用
在 体外 和 体内 研究中，桔皮素通过调节几种癌症类型中的不同途径来发挥其抗癌作用。它还具有抗氧化、抗炎和雌激素特性。
桔皮素是一种在柑橘类水果皮中发现的黄酮类化合物，它最有可能对真菌产生天然抗性。 桔皮素已被证明可以抵消肿瘤启动子诱导的细胞间通讯抑制，并可抑制几种癌症细胞的细胞增殖。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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