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Merck
CN

TRUEPVAF

TrueGel3D聚合物

modified for fast gelling (FAST-PVA)

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关于此项目

NACRES:
NA.71
UNSPSC Code:
12352207
Biological source:
synthetic
Technique(s):
cell attachment: suitable

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biological source

synthetic

technique(s)

cell attachment: suitable

shipped in

dry ice

storage temp.

−70°C

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General description

PVA polymers are functionalized with thiol-reactive maleimide groups, which react rapidly with thiol groups of crosslinkers to form hydrogels in few seconds. The thiol-reactive maleimide groups are also compatible to conjugate polymers with bioactive factors. The thioglycerol is used to maintain hydrogel strength and also as a control to compare cellular behavior in peptide-modified versus unmodified hydrogels. The buffers (pH7.2 and pH 5.5) are used to control pH and osmotic conditions to optimize time for gelation.

Application

FAST-PVA polymer is used with crosslinkers (CD/PEG crosslinkers) to establish stable hydrogels.

Features and Benefits

  • Contains synthetic polymer (PVA) functionalized with maleimide groups for quick gelation
  • Non degradable polymer

Other Notes

TRUEPVAF contains FAST-PVA solution in phosphate buffer, TrueGel3D thioglycerol and water.

Disclaimer

Avoid frequent freeze-thaw cycles and store FAST-PVA polymer in small portions.

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

存储类别

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0001615176

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商品

TrueGel3D™ Hydrogel for 3D Cell Culture

TrueGel3D™ is a synthetic hydrogels platform for 3D cell culture that aim to mimic the natural extracellular environment for more physiological culture conditions

True Gel3D™ Hydrogel Troubleshooting

Troubleshoot TrueGel3D™ hydrogel formation and cell viability issues with RGD-degradable polymer and CD cell-degradable crosslinker.

3D细胞培养水凝胶_细胞培养_TrueGel3D™水凝胶-默克生命科学

TrueGel3D™细胞培养水凝胶是一种由混合聚合物与交联剂混合而成的生化成分限定的水凝胶。与其他基于动物细胞生物提取物（例如小鼠EHS肿瘤细胞）的水凝胶相比，TrueGel3D™细胞培养水凝胶不含任何可能会干扰或造成实验污染的动物源成分。

实验方案

Advanced Protocol: How to Customize your TrueGel3D™ Hydrogel

An advanced protocol is available for TrueGel 3D kits for 3D cell culture for peptides concentration or stiffness optimisation

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