U100
乌拉地尔 盐酸盐
solid
别名:
6-[[3-[4-（o-甲氧苯基）-1-哌嗪基] 丙基] 氨基]-1,3-二甲基尿嘧啶 盐酸盐
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关于此项目
经验公式（希尔记法）:
C20H29N5O3 · HCl
化学文摘社编号:
分子量:
423.94
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), HTR1A(3350)
InChI key
KTMLZVUAXJERAT-UHFFFAOYSA-N
SMILES string
Cl[H].COc1ccccc1N2CCN(CCCNC3=CC(=O)N(C)C(=O)N3C)CC2
InChI
1S/C20H29N5O3.ClH/c1-22-18(15-19(26)23(2)20(22)27)21-9-6-10-24-11-13-25(14-12-24)16-7-4-5-8-17(16)28-3;/h4-5,7-8,15,21H,6,9-14H2,1-3H3;1H
form
solid
color
white
solubility
H2O: soluble 25 mg/mL, clear, colorless to very faintly yellow
General description
肾上腺受体 α1a 基因 (ADRA1A) 定位于人类染色体 8p21.2，编码 α-肾上腺素能受体。
Biochem/physiol Actions
α1-肾上腺素受体拮抗剂；5-HT1A 5-羟色胺受体部分激动剂；抗高血压。
肾上腺素受体 α1a 基因 (ADRA1A) 参与平滑肌收缩。全身血管如皮肤、胃肠系统、泌尿生殖系统、肾和脑的血管收缩也需要它。ADRA1A 在肝脏脂肪组织糖原分解和糖异生中起主要作用。对交感神经系统也起关键作用。
肾上腺素受体 α1a 基因 (ADRA1A) 参与平滑肌收缩。全身血管如皮肤、胃肠系统、泌尿生殖系统、肾和脑的血管收缩也需要它。ADRA1A 在肝脏脂肪组织糖原分解和糖异生中起主要作用。对交感神经系统也起关键作用。
Preparation Note
盐酸乌拉地尔溶于水，浓度为 25 mg/mL，得到澄清、无色至非常淡黄色溶液。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
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