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Merck
CN

U1006

Sigma-Aldrich

尿苷-5′-三磷酸酯 三钠盐 溶液

HPLC purified, aqueous solution for RNA polymerase transcription

别名:

UTP

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关于此项目

MDL编号:
MFCD00044310
UNSPSC代码:
41106305
PubChem化学物质编号:
24900622
NACRES:
NA.52

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生物来源

yeast (Candida Utilis)

方案

≥95 (HPLC)

表单

liquid

浓度

100 mM in H2O (adjusted to pH 7 with Trizma®
base)

颜色

colorless

异质活性

DNase and RNase, none detected

运输

dry ice

储存温度

−20°C

SMILES字符串

[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1

InChI key

MMJGIWFJVDOPJF-LLWADOMFSA-K

基因信息

human ... P2RY2(5029)
rat ... P2ry2(29597)

相关类别

应用

尿苷5′-三磷酸三钠盐溶液已用于增加大鼠原代气管上皮细胞中细胞内Ca2+水平。它还用作核苷酸底物，以分析MutT同源物1（MTH1）的活性。

生化/生理作用

P2Y受体激动剂
UTP参与RNA合成，在转录过程中具有至关重要的作用。它与糖原合成、蛋白质糖基化和膜磷脂生物合成有关。UTP 参与 ATP 的生产，而 ATP 对代谢反应至关重要。
尿苷5′-三磷酸（UTP）会在神经损伤时释放，并用作存在于雪旺细胞表面的嘌呤P2Y2受体的激动剂。

法律信息

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000494158
0000494158
0000375452
0000375452
SLCN0184

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