U1128
尿嘧啶
BioReagent, suitable for cell culture
别名:
2,4(1H,3H)-嘧啶二酮, 2,4-二羟基嘧啶, 灭胞素
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关于此项目
经验公式（希尔记法）:
C4H4N2O2
化学文摘社编号:
分子量:
112.09
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-621-9
Beilstein/REAXYS Number:
507828
MDL number:
产品名称
尿嘧啶, BioReagent, suitable for cell culture
InChI key
ISAKRJDGNUQOIC-UHFFFAOYSA-N
InChI
1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
SMILES string
O=C1NC=CC(=O)N1
biological source
synthetic (organic)
product line
BioReagent
assay
≥99% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
mp
>300 °C (lit.)
solubility
1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.
room temp
Quality Level
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Application
尿嘧啶已用作完全合成培养基1×、合成完全葡萄糖基酵母培养基（SC）和酵母提取物（YES）培养基的补充物，用于培养酵母细胞。
Biochem/physiol Actions
尿嘧啶及其衍生物在合成癌症、病毒感染、常染色体隐性遗传病、甲状腺和糖尿病药物的药物化学中不可或缺。
General description
尿嘧啶属于嘧啶碱基家族。它是天然存在的，是RNA重要而活跃的一部分。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Deepthi Ramesh et al.
European journal of medicinal chemistry, 207, 112801-112801 (2020-09-15)
Uracil is one of the most notable pharmacophores in medicinal chemistry as the pyrimidine nucleobase forms an integral part of many commercial drugs. Though the name uracil is usually associated with cancer drugs, there are many uracil-based compounds which can
Daisuke Katagiri et al.
Journal of the American Society of Nephrology : JASN, 24(12), 2034-2043 (2013-10-05)
Accumulating evidence of the beyond-glucose lowering effects of a gut-released hormone, glucagon-like peptide-1 (GLP-1), has been reported in the context of remote organ connections of the cardiovascular system. Specifically, GLP-1 appears to prevent apoptosis, and inhibition of dipeptidyl peptidase-4 (DPP-4)
Sandra M Carvalho et al.
PloS one, 8(3), e58492-e58492 (2013-03-19)
Links between carbohydrate metabolism and virulence in Streptococcus pneumoniae have been recurrently established. To investigate these links further we developed a chemically defined medium (CDM) and standardized growth conditions that allowed for high growth yields of the related pneumococcal strains
Morgane Auboiron et al.
STAR protocols, 2(2), 100557-100557 (2021-06-08)
Tracking the inheritance patterns of proteins (TrIPP) is a live-cell imaging technique used for tracking maternal protein segregation patterns between mother and daughter cells during asymmetric divisions of budding yeast. We use the photo-convertible fluorescent protein Dendra2 fused to a
William B White et al.
The New England journal of medicine, 369(14), 1327-1335 (2013-09-03)
To assess potentially elevated cardiovascular risk related to new antihyperglycemic drugs in patients with type 2 diabetes, regulatory agencies require a comprehensive evaluation of the cardiovascular safety profile of new antidiabetic therapies. We assessed cardiovascular outcomes with alogliptin, a new
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