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Merck
CN

U1128

尿嘧啶

BioReagent, suitable for cell culture

别名:

2,4(1H,3H)-嘧啶二酮, 2,4-二羟基嘧啶, 灭胞素

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关于此项目

经验公式(希尔记法):
C4H4N2O2
化学文摘社编号:
分子量:
112.09
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-621-9
Beilstein/REAXYS Number:
507828
MDL number:
Assay:
≥99% (HPLC)
Biological source:
synthetic (organic)
Form:
powder
Solubility:
1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
Storage temp.:
room temp
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biological source

synthetic (organic)

Quality Level

product line

BioReagent

assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

>300 °C (lit.)

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

room temp

SMILES string

O=C1NC=CC(=O)N1

InChI

1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)

InChI key

ISAKRJDGNUQOIC-UHFFFAOYSA-N

General description

尿嘧啶属于嘧啶碱基家族。它是天然存在的,是RNA重要而活跃的一部分。

Application

尿嘧啶已用作完全合成培养基1×、合成完全葡萄糖基酵母培养基(SC)和酵母提取物(YES)培养基的补充物,用于培养酵母细胞。

Biochem/physiol Actions

尿嘧啶及其衍生物在合成癌症、病毒感染、常染色体隐性遗传病、甲状腺和糖尿病药物的药物化学中不可或缺。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Deepthi Ramesh et al.
European journal of medicinal chemistry, 207, 112801-112801 (2020-09-15)
Uracil is one of the most notable pharmacophores in medicinal chemistry as the pyrimidine nucleobase forms an integral part of many commercial drugs. Though the name uracil is usually associated with cancer drugs, there are many uracil-based compounds which can
Brian T Wilhelm et al.
Nature protocols, 5(2), 255-266 (2010-02-06)
Next-generation sequencing technologies are revolutionizing genomics research. It is now possible to generate gigabase pairs of DNA sequence within a week without time-consuming cloning or massive infrastructure. This technology has recently been applied to the development of 'RNA-seq' techniques for
Sandra M Carvalho et al.
PloS one, 8(3), e58492-e58492 (2013-03-19)
Links between carbohydrate metabolism and virulence in Streptococcus pneumoniae have been recurrently established. To investigate these links further we developed a chemically defined medium (CDM) and standardized growth conditions that allowed for high growth yields of the related pneumococcal strains



全球贸易项目编号

货号GTIN
U1128-25G04061837404122
U1128-100G04061837404108