U2625
尿酸
≥99%, crystalline
别名:
2,6,8-三羟基嘌呤
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关于此项目
经验公式（希尔记法）:
C5H4N4O3
化学文摘社编号:
分子量:
168.11
UNSPSC Code:
12352005
NACRES:
NA.55
PubChem Substance ID:
EC Number:
200-720-7
Beilstein/REAXYS Number:
156158
MDL number:
产品名称
尿酸, ≥99%, crystalline
InChI key
LEHOTFFKMJEONL-UHFFFAOYSA-N
InChI
1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
SMILES string
O=C1NC(=O)C2=C(N1)NC(=O)N2
assay
≥99%
form
crystalline
mp
>300 °C (lit.)
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Application
尿酸可以用于：
- 诱导小鼠高尿酸血症
- 作为刺激体外人消化模型的消化液组分
- 选择性检测基于汗液的糖尿病监测葡萄糖感应器
Biochem/physiol Actions
尿酸是一种腺嘌呤和鸟嘌呤产生的不溶性分解代谢物。尿酸积累导致痛风，高尿酸血症，关节炎和肾功能衰竭。尿酸水平升高导致高血压与心血管疾病发病。低尿酸水平和帕金森症和多发性硬化有关，可能引发保护性功能。慢性阻塞性肺（COPD）病人高水平尿酸可用作潜在诊疗标记物。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Uric acid, hyperuricemia and vascular diseases
Jin M, et al.
Frontiers in Bioscience, 17, 656-656 (2012)
Serum uric acid as a predictor of mortality and future exacerbations of COPD
Bartziokas K, et al.
The European Respiratory Journal, 43(1), 43-53 (2014)
Uric acid in plants and microorganisms: Biological applications and genetics-A review
Hafez RM, et al.
Journal of Advanced Research, 8(5), 475-486 (2017)
A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy
Lee H, et al.
Nature Nanotechnology, 11(6), 566-566 (2016)
Serum uric acid: a risk factor and a target for treatment?
Feig DI, et al.
Journal of the American Society of Nephrology, 17(4), S69-S73 (2006)
商品
Uric acid present in animal sera impacts serum-supplemented classical cell culture systems, influencing cell culture performance.
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