U6381
尿核甙
≥99%, synthetic (organic), powder
别名:
尿苷, 尿嘧啶-1-β-D-呋喃核糖苷
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关于此项目
经验公式（希尔记法）:
C9H12N2O6
化学文摘社编号:
分子量:
244.20
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
200-407-5
MDL number:
Beilstein/REAXYS Number:
754902
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
H2O: 0.1 M, clear, colorless
产品名称
尿核甙, BioUltra, ≥99%
InChI key
DRTQHJPVMGBUCF-XVFCMESISA-N
InChI
1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
biological source
synthetic (organic)
product line
BioUltra
assay
≥99%
form
powder
impurities
≤0.016% Phosphorus (P), ≤0.1% Insoluble matter
ign. residue
≤0.2%
Quality Level
Gene Information
mouse ... Uck1(22245)
solubility
H2O: 0.1 M, clear, colorless
cation traces
Al: ≤0.0005%, Ca: ≤0.01%, Cu: ≤0.0005%, Fe: ≤0.003%, K: ≤0.005%, Mg: ≤0.003%, NH4+: ≤0.15%, Na: ≤0.02%, Pb: ≤0.005%, Zn: ≤0.0005%
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General description
尿苷是一种嘧啶核苷，对 RNA 和膜的合成至关重要。它通过形成嘧啶核苷酸-脂质缀合物来帮助正常细胞功能和生长。
Application
尿苷已被用于研究原生动物寄生虫的核苷水解酶和哺乳动物尿苷磷酸化酶在酿酒酵母的URH1（尿苷水解酶）上的功能互补。
它已用于检查长期应用尿苷对小鼠肝脏代谢的影响。
它已用于检查长期应用尿苷对小鼠肝脏代谢的影响。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Saccharomyces cerevisiae URH1 (encoding uridine-cytidine N-ribohydrolase): functional complementation by a nucleoside hydrolase from a protozoan parasite and by a mammalian uridine phosphorylase.
Mitterbauer R, et al.
Applied and Environmental Microbiology, 68, 1336-1343 (2002)
Purinergic and Pyrimidinergic Signalling: Molecular, Nervous and Urogenitary System Function
Handbook of Experimental Pharmacology (2013)
Chronic Uridine Administration Induces Fatty Liver and Pre-Diabetic Conditions in Mice.
Urasaki Y, et al.
PLoS ONE, 11, e0146994-e0146994 (2016)
Qi Qiu et al.
Nature methods, 17(10), 991-1001 (2020-09-02)
Single-cell RNA sequencing offers snapshots of whole transcriptomes but obscures the temporal RNA dynamics. Here we present single-cell metabolically labeled new RNA tagging sequencing (scNT-seq), a method for massively parallel analysis of newly transcribed and pre-existing mRNAs from the same
Juma A M Ali et al.
Molecular pharmacology, 83(2), 439-453 (2012-11-29)
African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host. However, uptake of pyrimidines in bloodstream form trypanosomes has not been investigated, making it difficult to judge the relative importance of salvage and synthesis
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