U9257
UbcH9 Conjugating Enzyme human
≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution
产品名称
UbcH9 Conjugating Enzyme human, ≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution
recombinant
expressed in E. coli
assay
≥95% (SDS-PAGE)
form
buffered aqueous glycerol solution
shipped in
dry ice
storage temp.
−70°C
Quality Level
Gene Information
human ... UBE2E3(10477), UBE2I(7329)
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Biochem/physiol Actions
UbcH9 mediates the conjugation of SUMO-1, SUMO-2, and SUMO-3 to a diverse variety of proteins without the help of an E3 ligase. This E2 conjugating enzyme interacts directly with protein substrates that are modified by SUMOylation, and may help in substrate recognition. UbcH9 is specific for the conjugation of proteins modified by SUMOylation.
General description
Manufactured for Sigma by Boston Biochem., Inc.
Physical form
Solution in 50 mM HEPES, pH 7.5, 100 mM NaCl, 10 % glycerol, 1mM TCEP.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
J M Desterro et al.
FEBS letters, 417(3), 297-300 (1997-12-31)
Ubiquitin conjugating enzymes participate in the thioester cascade that leads to protein ubiquitination. Although Ubc9 is homologous to E2 ubiquitin conjugating enzymes we have shown that it is unable to form a thioester with ubiquitin, but can form a thioester
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