U9507
Urocortin II mouse
别名:
UCN-II
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关于此项目
Form:
solid
Assay:
≥97% (HPLC)
Biological source:
mouse
biological source
mouse
Quality Level
assay
≥97% (HPLC)
form
solid
technique(s)
immunohistochemistry: suitable
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Ucn2(171530)
Application
Mouse urocortin II can be used for immunohistochemistry.
Biochem/physiol Actions
Urocortin II is a CRF-related neuropeptide having high affinity for CRF2 receptor. It stimulates protein kinase A through CRF2 receptor and increases the contractility in rabbit ventricular myocytes. It also facilitates pro-inflammatory effects in human intestinal cells through corticotropin-releasing hormone receptor 2α.
corticotropin-releasing factor (CRF) peptide
Other Notes
Lyophilized from 0.1% TFA in H2O
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Alan C Moss et al.
Gut, 56(9), 1210-1217 (2007-04-07)
Urocortin II (UcnII) is a neuropeptide that binds with high affinity to the corticotropin-releasing hormone receptor 2 (CRHR2) in peripheral tissues. UcnII is synthesised in the intestine, but its role in human intestinal inflammation is largely unknown. Responses of human
Li-Zhen Yang et al.
Cardiovascular research, 69(2), 402-411 (2006-01-03)
Urocortin II (UcnII), a peptide of the corticotropin-releasing factor (CRF) family, exerts profound actions on the cardiovascular system. Direct effects of UcnII on adult cardiomyocytes have not been evaluated before. Our aim was to characterize functional effects of UcnII on
David P Burns et al.
The Journal of physiology, 596(21), 5175-5197 (2018-08-31)
Impaired ventilatory capacity and diaphragm muscle weakness are prominent features of Duchenne muscular dystrophy, with strong evidence of attendant systemic and muscle inflammation. We performed a 2-week intervention in young wild-type and mdx mice, consisting of either injection of saline
Dimitri Tränkner et al.
Cell reports, 29(4), 791-799 (2019-10-24)
Aberrant microglia activity is associated with many neurological and psychiatric disorders, yet our knowledge about the pathological mechanisms is incomplete. Here, we describe a genetically defined microglia sublineage in mice which has the ability to suppress obsessive compulsion and anxiety symptoms. These
David P Burns et al.
Experimental physiology, 102(9), 1177-1193 (2017-07-01)
What is the central question of this study? We previously reported impaired upper airway dilator muscle function in the mdx mouse model of Duchenne muscular dystrophy (DMD). Our aim was to assess the effect of blocking interleukin-6 receptor signalling and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| U9507-500UG | 04061832678122 |
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