Product Name
(S)-(−)-华法林, ≥97% (HPLC)
方案
≥97% (HPLC)
表单
solid
颜色
white to pale yellow
mp
≥170 °C
储存温度
2-8°C
SMILES字符串
[H][C@](CC(C)=O)(c1ccccc1)C2=C(O)c3ccccc3OC2=O
InChI
1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3/t15-/m0/s1
InChI key
PJVWKTKQMONHTI-HNNXBMFYSA-N
基因信息
human ... CYP2C9(1559)
一般描述
Warfarin is an antagonist of vitamin K. It is an oral coumarin anticoagulant.
应用
(S)-(−)-Warfarin has been used in cell cultures.
Studies using (R)-(+)-warfarin have reported that it can upregulate hepatic CYP3A4 and CYP2C. It has also been used in HepG2 cells to study protein profiles.
生化/生理作用
CYP2C9 substrate; anticoagulant.
Warfarin is used to regulate and inhibit thromboembolic disorders. The CYP2C9 (cytochrome P450 family 2 subfamily C member 9) protein plays a major role in the inactivation of potent S-warfarin.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
警示用语：
Danger
危险分类
Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Repr. 1A - STOT RE 1
靶器官
Blood
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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