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UC263

7-Hydroxycoumarin glucuronide sodium salt

Actin polymerization inhibitor, solid

别名:

7-Hydroxy-2H-1-benzopyran-2-one glucuronide sodium salt, Umbelliferone glucuronide sodium salt

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关于此项目

经验公式（希尔记法）:
C15H13NaO9
化学文摘社编号:
66695-14-5
分子量:
360.25
UNSPSC Code:
12161501
PubChem Substance ID:
24724651
NACRES:
NA.77
MDL number:
MFCD00674902
Form:
solid
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产品名称

7-Hydroxycoumarin glucuronide sodium salt,

form

solid

color

white to faint yellow

mp

≥285 °C

storage temp.

2-8°C

SMILES string

[Na+].O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C([O-])=O)Oc2ccc3C=CC(=O)Oc3c2

InChI

1S/C15H14O9.Na/c16-9-4-2-6-1-3-7(5-8(6)23-9)22-15-12(19)10(17)11(18)13(24-15)14(20)21;/h1-5,10-13,15,17-19H,(H,20,21);/q;+1/p-1/t10-,11-,12+,13-,15+;/m0./s1

InChI key

SKHLGBDGEPDEME-KSOKONAESA-M

Application

7-Hydroxycoumarin glucuronide sodium salt can be used as a standard for the analysis of 7-hydroxycoumarin metabolites.
Phase II (UDP-GT) metabolite of 7-hydroxycoumarin.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000178478
0000178478
0000126432
0000135911
0000126433

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U S Weber et al.
Research communications in molecular pathology and pharmacology, 99(2), 193-206 (1998-05-16)
Coumarin is found in many medicinal plants and therefore also used in phytomedicine for the treatment of venous diseases. The metabolic pathways of coumarin in the human body lead to the intermediate 7-hydroxy-coumarin and consequent glucuronidation in the intestine and
J G Conway et al.
The Biochemical journal, 226(3), 749-756 (1985-03-15)
The effect of starvation and glucose addition on glucuronidation was assessed in sublobular regions of the lobule in perfused livers from phenobarbital-treated rats. Fibre-optic micro-light guides were placed on periportal and pericentral areas on the surface of livers to monitor
Y N Cha et al.
Chemico-biological interactions, 61(2), 125-137 (1987-02-01)
Functional relationship between the initial mixed function oxidation of 7-ethoxycoumarin (EC) to 7-hydroxycoumarin (HC) and the subsequent conjugation of this metabolite to sulfate ester and glucuronide has been studied using isolated perfused rat livers. When increasing concentrations of EC (from
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全球贸易项目编号

货号GTIN
UC263-10MG04061832932088
UC263-5MG04061832932095