UC304
O -去甲基曲马多
别名:
2-[（二甲氨基）甲基]-1-（3-羟基苯基）环己醇, O -去甲基曲马多
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关于此项目
经验公式（希尔记法）:
C15H23NO2
化学文摘社编号:
分子量:
249.35
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12161501
MDL number:
InChI
1S/C15H23NO2/c1-16(2)11-13-6-3-4-9-15(13,18)12-7-5-8-14(17)10-12/h5,7-8,10,13,17-18H,3-4,6,9,11H2,1-2H3/t13-,15+/m1/s1
SMILES string
CN(C)C[C@H]1CCCC[C@]1(O)c2cccc(O)c2
InChI key
UWJUQVWARXYRCG-HIFRSBDPSA-N
form
solid
storage temp.
2-8°C
Application
O -去甲基曲马多已用于曲马多代谢物在山羊体内的药代动力学研究 。
O-去甲基曲马多可用作阿片类药物，用于测试其对人类自然杀伤细胞的细胞毒性功能的影响。它也可用作气相色谱-质谱法（GC-MS）中的内标物，用于定量测定人尿液样品中的曲马多衍生物。
Biochem/physiol Actions
O-去甲基曲马多对阿片受体具有高亲和力，并导致μ阿片受体的镇痛作用。
曲马多的代谢产物
General description
O-去甲基曲马多是一种阿片类药物，同时也是曲马多的活性代谢物。其生产的关键酶是多态性细胞色素P450同工酶2D6（CYP2D6）。
Packaging
无底玻璃瓶。内含物装在插入的融合锥内。
flash_point_f
Not applicable
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
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Tramadol.
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