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关于此项目
经验公式(希尔记法):
C13H12O3
化学文摘社编号:
分子量:
216.23
UNSPSC Code:
12161501
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8838512
Form:
solid
Quality level:
form
solid
Quality Level
color
white
mp
182-183 °C
storage temp.
2-8°C
SMILES string
C[C@H](C(O)=O)c1ccc2cc(O)ccc2c1
InChI
1S/C13H12O3/c1-8(13(15)16)9-2-3-11-7-12(14)5-4-10(11)6-9/h2-8,14H,1H3,(H,15,16)/t8-/m0/s1
InChI key
XWJUDDGELKXYNO-QMMMGPOBSA-N
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Application
O-Desmethylnaproxen can be used for assaying naproxen metabolites.
Biochem/physiol Actions
CYP2C9 metabolite of naproxen
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
T B Vree et al.
Journal of chromatography, 578(2), 239-249 (1992-07-24)
Naproxen is metabolized in humans by O-demethylation, and by acyl glucuronidation to the 1-O-glucuronide. Naproxen, its metabolite and the conjugates can be measured directly by gradient high-performance liquid chromatographic analysis without enzymic deglucuronidation. The glucuronide conjugates were isolated by preparative
High-performance liquid chromatographic determination of 6-desmethylnaproxen sulfate in human plasma.
C H Kiang et al.
Journal of chromatography, 383(2), 449-455 (1986-12-19)
Amitava Dasgupta et al.
American journal of clinical pathology, 133(6), 878-883 (2010-05-18)
A recent report indicated significant interference of naproxen with total bilirubin measurement when using the Jendrassik and Grof method. We explored the possibility of avoiding this interference by using a different method. We observed that naproxen has no effect on
Hypoalbuminaemia and naproxen pharmacokinetics in a patient with rheumatoid arthritis.
F A Van den Ouweland et al.
Clinical pharmacokinetics, 11(6), 511-515 (1986-11-01)
C E Uboh et al.
Research communications in chemical pathology and pharmacology, 77(2), 201-218 (1992-08-01)
This study was undertaken to determine the applicability of plasma concentration of furosemide and specific gravity (SG) of urine in regulating the use of furosemide administered 4 hours prior to race time in Exercise-Induced Pulmonary Hemorrhage (EIPH) race horses. Nonbleeders
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| UC305-5MG | 04061832932170 |
| UC305-10MG | 04061832932163 |
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