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Merck
CN

V0131

Vasoactive Intestinal Peptide Fragment 1-12 human, porcine, rat

≥97% (HPLC)

别名:

VIP 1-12

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关于此项目

经验公式(希尔记法):
C61H88N18O22
化学文摘社编号:
分子量:
1425.46
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.26
MDL number:
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产品名称

Vasoactive Intestinal Peptide Fragment 1-12 human, porcine, rat, ≥97% (HPLC)

Quality Level

assay

≥97% (HPLC)

form

solid

UniProt accession no.

application(s)

cell analysis

storage temp.

−20°C

SMILES string

CC(C)C(NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(Cc2ccccc2)C(=O)NC(C(C)O)C(=O)NC(CC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(C(C)O)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C61H88N18O22/c1-27(2)46(77-49(89)28(3)69-51(91)40(22-44(85)86)73-56(96)42(25-80)76-50(90)35(62)20-33-24-66-26-68-33)57(97)74-38(18-31-10-7-6-8-11-31)55(95)79-48(30(5)82)59(99)75-41(23-45(87)88)53(93)72-39(21-43(63)84)52(92)71-37(19-32-13-15-34(83)16-14-32)54(94)78-47(29(4)81)58(98)70-36(60(100)101)12-9-17-67-61(64)65/h6-8,10-11,13-16,24,26-30,35-42,46-48,80-83H,9,12,17-23,25,62H2,1-5H3,(H2,63,84)(H,66,68)(H,69,91)(H,70,98)(H,71,92)(H,72,93)(H,73,96)(H,74,97)(H,75,99)(H,76,90)(H,77,89)(H,78,94)(H,79,95)(H,85,86)(H,87,88)(H,100,101)(H4,64,65,67)

InChI key

OZQVVUDUPMJWPH-UHFFFAOYSA-N

Gene Information

human ... VIP(7432)

Biochem/physiol Actions

Ligand for CD4 receptor.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

此项目有


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K J Sung et al.
Neuropeptides, 33(6), 435-446 (2000-02-05)
It is well known that psoriasis, an immunogenetic cutaneous disorder whose major pathogenic findings are epidermal hyperplasia and T-cell infiltration, is aggravated by psychological stresses. Although the exact mechanism is not yet clarified, antidromic secretion of neuropeptides by cutaneous nerve
M Ichinose et al.
Regulatory peptides, 54(2-3), 457-466 (1994-12-15)
The effect of VIP on phagocytosis in peritoneal macrophages was examined by means of flow cytometry (FCM). This assay revealed that VIP suppressed phagocytosis in a dose-dependent manner. VIP(1-12) did not suppress phagocytosis. VIP(10-28) was more suppressive than VIP(1-28). A
S Chakder et al.
The Journal of pharmacology and experimental therapeutics, 266(1), 392-399 (1993-07-01)
Because no significant information exists regarding the structure-activity of vasoactive intestinal polypeptide (VIP) to gut smooth muscle, we performed functional studies in vitro on opossum internal anal sphincter (IAS) smooth muscle strips and supplemented them with binding studies to assess
F Séjourné et al.
The American journal of physiology, 273(1 Pt 2), R287-R292 (1997-07-01)
The purpose of this study was to begin to determine the mechanisms underlying vasodilation elicited by vasoactive intestinal peptide (VIP) in sterically stabilized liposomes (SSL) in the in situ peripheral microcirculation. Using intravital microscopy, we found that suffusion of VIP
P Sacerdote et al.
Journal of neuroscience research, 18(1), 102-107 (1987-01-01)
A five-amino-acid (TDNYT) sequence of vasoactive intestinal polypeptide (VIP) shares homology with the proposed attachment sequences of the human immunodeficiency virus (HIV). Synthetic peptides with these sequences have previously been shown to block viral envelope (gp120) binding and HIV infectivity

全球贸易项目编号

货号GTIN
V0131-.1MG04061832823010
V0131-1MG04061826286326

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