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Merck
CN

V1253

Anti-Vascular Endothelial Growth Factor antibody produced in goat

affinity isolated antibody, lyophilized powder

别名:

Anti-VEGF

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UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
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产品名称

Anti-Vascular Endothelial Growth Factor antibody produced in goat, affinity isolated antibody, lyophilized powder

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse

technique(s)

capture ELISA: suitable
immunohistochemistry: suitable
neutralization: suitable
western blot: suitable

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

mouse ... Vegfa(22339)

Application

Anti-Vascular Endothelial Growth Factor antibody can be used in sandwich ELISAs as a capture antibody in mouse VEGF 164 or 120. It can also be used in immunohistochemistry.

Biochem/physiol Actions

The antibody will neutralize the biological activity of recombinant mouse VEGF164, and recombinant mouse VEGF121. It can also be used as a capture antibody in mouse VEGF 164 or 120 sandwich ELISAs.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Vascular Endothelial Growth Factor (VEGF) is a 46kD dimeric, heparin binding glycoprotein. It facilitates several functions like induction of endothelial cell proliferation, inhibits apoptosis, induces permeabilization of blood vessels and promotes cell migration. Anti-Vascular Endothelial Growth Factor antibody can be used for neutralizing the biological activity of recombinant mouse (VEGF164) and recombinant mouse (VEGF120). It can also be used in immunoblotting. Goat anti-Vascular Endothelial Growth Factor antibody reacts specifically with recombinant mouse VEGF.

Immunogen

purified 164 amino acid residue variant of recombinant mouse VEGF.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Merve Nur Eğlenen et al.
Turkish journal of orthodontics, 36(2), 79-86 (2023-06-22)
Functional treatment of Class II malocclusion is expected to lead to adaptation in the condyle. This study aimed to evaluate the effects of adipose tissue-derived mesenchymal stem cells (ADMSCs), low-level laser therapy (LLLT), and grape-seed extract (GSE) on condylar growth
Dorien Reijnders et al.
Physiological genomics, 50(5), 385-392 (2018-03-10)
Preeclampsia (PE), a hypertensive disease of pregnancy, is a leading cause of fetal and maternal morbidity/mortality. Early angiogenic and inflammatory disturbances within the placenta are thought to underlie the development of the maternal PE syndrome and poor pregnancy outcomes. However
Johan Dixelius et al.
Cancer research, 66(4), 2089-2097 (2006-02-21)
Histidine-rich glycoprotein (HRGP) is an abundant heparin-binding plasma protein that efficiently arrests growth and vascularization of mouse tumor models. We have shown that the antiangiogenic effect of HRGP is dependent on its histidine/proline-rich domain, which needs to be released from
Jeanette Woolard et al.
Cancer research, 64(21), 7822-7835 (2004-11-03)
Growth of new blood vessels (angiogenesis), required for all tumor growth, is stimulated by the expression of vascular endothelial growth factor (VEGF). VEGF is up-regulated in all known solid tumors but also in atherosclerosis, diabetic retinopathy, arthritis, and many other
Vascular endothelial growth factor induces cyclooxygenase-dependent proliferation of endothelial cells via the VEGF-2 receptor.
J F Murphy et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 15(9), 1667-1669 (2001-06-28)

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