V2889
Valeryl Salicylate
≥98% (HPLC)
别名:
2-Valeryloxybenzoic acid, Valerylsalicylic acid, vsa
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关于此项目
经验公式（希尔记法）:
C12H14O4
CAS Number:
分子量:
222.24
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98% (HPLC)
表单
solid
颜色
white
mp
86-87 °C (lit.)
溶解性
DMSO: 24 mL/mL
H2O: insoluble
SMILES字符串
CCCCC(=O)Oc1ccccc1C(O)=O
InChI
1S/C12H14O4/c1-2-3-8-11(13)16-10-7-5-4-6-9(10)12(14)15/h4-7H,2-3,8H2,1H3,(H,14,15)
InChI key
WJHZBTMHUNVIKC-UHFFFAOYSA-N
相关类别
生化/生理作用
Selective, irreversible COX-1 inhibitor. The selectivity for COX-1 vs COX-2 shows the IC50 values for ovine COX-1 vs COX-2 of 0.8 μM vs. 15 mM respectively.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
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Pulmonary circulation, 9(4), 2045894019895947-2045894019895947 (2020-01-08)
Epoxyeicosatrienoic acids (EETs) are synthesized from arachidonic acid by CYP/epoxygenase and metabolized by soluble epoxide hydrolase (sEH). Roles of EETs in hypoxia-induced pulmonary hypertension (HPH) remain elusive. The present study aimed to investigate the underlying mechanisms, by which EETs potentiate
Jing Huang et al.
Pulmonary circulation, 9(1), 2045894019837876-2045894019837876 (2019-02-27)
Caveolin-1 (cav-1) has been shown to play a significant role in the pathogenesis of pulmonary hypertension (PH). In the monocrotaline model of PH, the loss of endothelial cav-1 as well as reciprocal activation of proliferative and anti-apoptotic pathways initiate the
Eduardo Candelario-Jalil et al.
Journal of neuroinflammation, 4, 25-25 (2007-10-12)
Neuroinflammatory responses are triggered by diverse ethiologies and can provide either beneficial or harmful results. Microglial cells are the major cell type involved in neuroinflammation, releasing several mediators, which contribute to the neuronal demise in several diseases including cerebral ischemia
Cai Liang et al.
Biochemical pharmacology, 159, 11-24 (2018-11-11)
Augmented endothelium-dependent contractions (EDC) contributes to endothelial dysfunction and vascular disease progression. An early signal in EDC is cytosolic [Ca2+]i rise in endothelial cells, which stimulates the production of contractile prostanoids, leading to vascular contraction. In this study, the molecular
Karina Cristina Giannotti et al.
Scientific reports, 7(1), 4098-4098 (2017-06-24)
Crotoxin B (CB) is a catalytically active group IIA sPLA
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