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Merck
CN

V4015

毛蕊花苷

≥99% (HPLC)

别名:

类叶升麻苷, 麦角甾苷

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关于此项目

经验公式(希尔记法):
C29H36O15
化学文摘社编号:
分子量:
624.59
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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Quality Level

assay

≥99% (HPLC)

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

room temp

SMILES string

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1

InChI key

FBSKJMQYURKNSU-ZLSOWSIRSA-N

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General description

毛蕊花苷,又称 毛蕊花糖苷,是一种亲水性植物化合物,首次从毛蕊花属植物中分离出来(Verbascum sinuatum L.)。毛蕊糖苷的化学结构包括羟基苯基乙基和肉桂酸部分,通过糖苷键与β-吡喃葡萄糖结合。

Application

毛蕊花苷已被:
  • 用作高效液相色谱分析(HPLC)的参考标准品
  • 用作参考标准品,通过高效液相色谱(HPLC)-二极管阵列检测器(DAD)-qTOF系统,对橄榄厂废水和废渣中酚类化合物进行检测
  • 在HEP2细胞和A549细胞中检测对呼吸道合胞病毒(RSV)的抗病毒活性

Biochem/physiol Actions

毛蕊花苷具有抗炎和光保护特性。它对PC12神经细胞具有神经毒性保护作用。在体外研究中,毛蕊花糖苷被证明是黄嘌呤氧化酶(XOD)的有效抑制剂。
苯乙醇苷。抗氧化和抗增殖。

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Guo-Qing Sheng et al.
European journal of pharmacology, 451(2), 119-124 (2002-09-17)
The neuroprotective effects of verbascoside, one of phenylpropanoid glucoside isolated from the Chinese herbal medicine Buddleja officinalis Maxim, on 1-methyl-4-phenylpyridinium ion (MPP(+)) induced apoptosis and oxidative stress in PC12 neuronal cells were investigated. Treatment of PC12 cells with MPP(+) for
Kiramage Chathuranga et al.
Viruses, 11(7) (2019-07-07)
The herbs Plantago asiatica and Clerodendrum trichotomum have been commonly used for centuries in indigenous and folk medicine in tropical and subtropical regions of the world. In this study, we show that extracts from these herbs have antiviral effects against
Augusto G Filho et al.
Phytotherapy research : PTR, 26(10), 1472-1475 (2012-01-26)
The phenylpropanoid glycoside verbascoside [2-(3,4-dihydroxyphenylethyl)-1-O-α-L-rhamnopyranosyl-(1→3)-β-D-(4-O-caffeyl)-glucopyranoside] (1) has been isolated as the main constituent of the crude extract of Buddleja brasiliensis Jacq. ex Spreng from Southern Brazil. The crude extract, main fractions and the compound 1 were evaluated for inhibition of
Luis Felipe Santos-Cruz et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(3-4), 1082-1090 (2011-12-27)
Verbascoside (VB) is a phenylpropanoid isolated from Buddleja species, some of which originate in Mexico, and was first described in the sixteenth century in the codices of Mexican traditional medicine. VB is present in alcohol extracts and is widely used
Hong-Quan Wang et al.
Neurotoxicity research, 21(4), 368-378 (2011-12-08)
Our previous study has shown that acteoside, an antioxidative phenylethanoid glycoside, protect against beta-amyloid (Aβ)-induced cytotoxicity in vitro. However, the precise protective mechanisms remains unclear. Heme oxygenase-1 (HO-1) is a crucial factor in the response to oxidative injury, protecting neurons

全球贸易项目编号

货号GTIN
V4015-10MG04061832402567

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