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V4508

Vasoactive Intestinal Peptide Fragment 6-28 human, porcine, rat

Name: Vasoactive Intestinal Peptide Fragment 6-28 human, porcine, rat
Brand: SIGMA

≥97% (HPLC)

别名:

VIP 6-28

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关于此项目

经验公式（希尔记法）:

C₁₂₆H₂₀₇N₃₇O₃₄S

化学文摘社编号:

69698-54-0

分子量:

2816.28

NACRES:

NA.32

PubChem Substance ID:

24900748

UNSPSC Code:

51111800

MDL number:

MFCD00237319

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Quality Level

200

assay

≥97% (HPLC)

UniProt accession no.

P01282, P01283

storage temp.

−20°C

SMILES string

CCC(C)C(NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(N)=N)NC(=O)C(NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(CC(N)=O)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(N)Cc3ccccc3)C(C)O)C(C)O)C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(N)=O)C(N)=O

InChI

1S/C126H207N37O34S/c1-15-66(10)99(122(195)157-86(53-64(6)7)113(186)150-83(102(135)175)57-94(132)170)161-120(193)92(61-164)159-117(190)90(59-96(134)172)155-114(187)85(52-63(4)5)152-115(188)87(55-71-34-38-73(167)39-35-71)153-109(182)77(30-20-23-46-128)144-107(180)78(31-21-24-47-129)148-121(194)98(65(8)9)160-103(176)67(11)142-105(178)82(44-50-198-14)147-111(184)81(42-43-93(131)169)146-106(179)76(29-19-22-45-127)143-108(181)79(32-25-48-140-125(136)137)145-112(185)84(51-62(2)3)151-110(183)80(33-26-49-141-126(138)139)149-123(196)101(69(13)166)163-119(192)88(56-72-36-40-74(168)41-37-72)154-116(189)89(58-95(133)171)156-118(191)91(60-97(173)174)158-124(197)100(68(12)165)162-104(177)75(130)54-70-27-17-16-18-28-70/h16-18,27-28,34-41,62-69,75-92,98-101,164-168H,15,19-26,29-33,42-61,127-130H2,1-14H3,(H2,131,169)(H2,132,170)(H2,133,171)(H2,134,172)(H2,135,175)(H,142,178)(H,143,181)(H,144,180)(H,145,185)(H,146,179)(H,147,184)(H,148,194)(H,149,196)(H,150,186)(H,151,183)(H,152,188)(H,153,182)(H,154,189)(H,155,187)(H,156,191)(H,157,195)(H,158,197)(H,159,190)(H,160,176)(H,161,193)(H,162,177)(H,163,192)(H,173,174)(H4,136,137,140)(H4,138,139,141)

InChI key

BVEZAVADHLXCKB-UHFFFAOYSA-N

Gene Information

human ... VIP(7432)
rat ... Vip(117064)

Biochem/physiol Actions

Potent VIP receptor antagonist

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Fishbein, V.A., et al.

Peptide, 15, 95-95 (1994)

Pituitary adenylate cyclase-activating polypeptide (PACAP) contributes to the proliferation of hematopoietic progenitor cells in murine bone marrow via PACAP-specific receptor.

Zhifang Xu et al.

Scientific reports, 6, 22373-22373 (2016-03-02)

Pituitary adenylate cyclase-activating polypeptide (PACAP, encoded by adcyap1) plays an important role in ectodermal development. However, the involvement of PACAP in the development of other germ layers is still unclear. This study assessed the expression of a PACAP-specific receptor (PAC1)

Polarized enteric submucosal circuits involved in secretory responses of the guinea-pig proximal colon.

M Neunlist et al.

The Journal of physiology, 506 ( Pt 2), 539-550 (1998-03-10)

1. Neuronal retrograde tracing with the dye DiI (1,1'-didodecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate), in combination with immunohistochemical detection of choline acetyltransferase (ChAT) and vasoactive intestinal peptide (VIP), were used to identify the innervation of the mucosa of the guinea-pig proximal colon by submucosal

Glucagon-like peptide-2 interferes with the neurally-induced relaxant responses in the mouse gastric strips through VIP release.

Chiara Traini et al.

Neuropeptides, 81, 102031-102031 (2020-03-08)

Glucagon-like peptide-2 (GLP-2) has been reported to indirectly relax gastric smooth muscle. In the present study we investigated, through a combined mechanical and immunohistochemical approach, whether GLP-2 interferes with the electrical field stimulation (EFS)-induced vipergic relaxant responses and the mechanism

Protective effects of vasoactive intestinal peptide against delayed glutamate neurotoxicity in cultured retina.

K Shoge et al.

Brain research, 809(1), 127-136 (1998-10-31)

The effects of vasoactive intestinal peptide (VIP) on glutamate-induced delayed death were examined using the primary cultures of rat retinal neurons. Effects of VIP on glutamate-induced neurotoxicity were evaluated by double staining with fluorescein diacetate and propidium iodide. Glutamate (1

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货号	GTIN
V4508-.5MG	04061832678160

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主要文件

Vasoactive Intestinal Peptide Fragment 6-28 human, porcine, rat

≥97% (HPLC)

选择尺寸

关于此项目

属性

Quality Level

assay

UniProt accession no.

storage temp.

SMILES string

InChI

InChI key

Gene Information

说明

Biochem/physiol Actions

安全信息

存储类别

wgk

flash_point_f

flash_point_c

ppe

法规信息

文件

分析证书(COA)

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