产品名称
Vascular Endothelial Growth Factor from mouse, VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture
biological source
mouse
Quality Level
recombinant
expressed in E. coli
assay
≥98% (SDS-PAGE)
form
powder
potency
≤10 ng/mL
quality
endotoxin tested
mol wt
protein 39 kDa
packaging
pkg of 10 μg, pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
<1 EU/μg
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... VEGFA(22339)
General description
Vascular endothelial growth factor is also known as VPF, VEGF and MVCD1. It is secreted from endothelial cells and pericytes in response to hypoxia. It helps in inducing angiogenesis and microvascular hyperpermeability. VEGF levels are associated with vasculitic neuropathy and may be used to predict this disease. It may also act as a marker in the development and progression of early precancerous lesions of oesophagus.
Application
Vascular endothelial growth factor (VEGF) supports development of new blood vessels during embryonic development and after vascular injury.Vascular endothelial growth factor from mouse was used for ELISA and in matrigel plugs (matrigel was supplemented with VEGF).
Physical form
Lyophilized from a 0.2 μm filtered buffered solution.
Analysis Note
The biological activity is measured by the ability to stimulate 3H-thymidine incorporation in human umbilical vein endothelial cells (HUVEC) and bovine aortic endothelial cells.
Other Notes
Homodimeric protein consisting of two 165 amino acid polypeptide chains of mouse VEGF.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
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VEGF-A stimulates blood vessel growth via endothelial cell proliferation, migration, and survival during embryonic development.
Katsuhisa Tashiro et al.
Stem cells and development, 23(18), 2202-2210 (2013-12-19)
Vascular endothelial growth factor (VEGF) is reported to exhibit potent hematopoietic stem/progenitor cell (HSPC) mobilization activity. However, the detailed mechanisms of HSPC mobilization by VEGF have not been examined. In this study, we investigated the effect of VEGF on bone
Asieh Golozar et al.
European journal of cancer (Oxford, England : 1990), 50(16), 2855-2865 (2014-08-31)
Mechanisms involved in wound healing play some role in carcinogenesis in multiple organs, likely by creating a chronic inflammatory milieu. This study sought to assess the role of genetic markers in selected inflammation-related genes involved in wound healing (interleukin (IL)-1a
Victor Manolov et al.
Clinical laboratory, 60(9), 1573-1577 (2014-10-09)
Vascular endothelial growth factor (VEGF) is secreted from endothelial cells and pericytes in response to hypoxia. It induces angiogenesis and microvascular hyperpermeability. We observe serum VEGF concentrations in some patients with vasculitic neuropathy. Plasma VEGF was measured using GenWay's human
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| V4512-10UG | 04061837481024 |
| V4512-50UG | 04061837481031 |