一般描述
This Human VPS34 (vacuolar protein sorting 34) protein has a N-terminal FLAG-tag, expressed in Sf9 insect cells via a baculovirus expression system.
应用
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
生化/生理作用
VPS34 was shown to be required for proper liver and heart function. Mice deficient in VPS34 develop hepatomegaly and cardiomegaly.
外形
Formulatedin a buffered solution consisting of 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2mM KCl, 80 μg/ml FLAG peptide, 20% glycerol., and 3 mM DTT.
其他说明
One unit will transfer one picomole of phosphate from ATP to a phospholipid mixture per minute at 30 °C at pH 7.4.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Nadia Jaber et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(6), 2003-2008 (2012-02-07)
A critical regulator of autophagy is the Class III PI3K Vps34 (also called PIK3C3). Although Vps34 is known to play an essential role in autophagy in yeast, its role in mammals remains elusive. To elucidate the physiological function of Vps34
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