Product Name
VEGF165, recombinant, expressed in HEK 293 cells, suitable for cell culture
生物来源
human
质量水平
重组
expressed in HEK 293 cells
描述
Vascular Endothelial Growth Factor 165 human
方案
≥95% (SDS-PAGE)
表单
lyophilized powder
效能
<10 ng/mL ED50
质量
endotoxin tested
分子量
dimer 42 kDa (glycosylated)
包装
pkg of 10 μg
pkg of 50 μg
技术
cell culture | mammalian: suitable
杂质
<0.075 EU/μg
颜色
white
溶解性
water: soluble
UniProt登记号
储存温度
−20°C
基因信息
human ... VEGFA(7422)
一般描述
VEGF165 is expressed in human HEK 293 cells as a glycosylated homodimer with an apparent molecular mass of 45 kDa. Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
生化/生理作用
VEGF165 belongs to the PDGF/VEGF growth factor family characterized by the presence of eight conserved cysteine residues and a cystine knot structure. VEGF is secreted by the majority of tumor cells and initiates angiogenesis by activating endothelial cells of existing blood vessels and promoting their migration.
VEGF has also been implicated in correlation with poor prognosis in breast cancer.
In addition, VEGF is released in rheumatoid arthritis in response to TNF-α, increasing endothelial permeability and stimulating angiogenesis (formation of capillaries).
VEGF has also been implicated in correlation with poor prognosis in breast cancer.
In addition, VEGF is released in rheumatoid arthritis in response to TNF-α, increasing endothelial permeability and stimulating angiogenesis (formation of capillaries).
分析说明
The specific activity was determined by the dose-dependent stimulation of the proliferation of HUVEC cells (human umbilical vein endothelial cells).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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