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Merck
CN

V7127

D-Val-Leu-Lys 对硝基苯胺 二盐酸盐

plasmin substrate, chromogenic, ≥98% (HPLC), powder

别名:

D-Val-Leu-Lys 对硝基苯胺

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关于此项目

经验公式(希尔记法):
C23H38N6O5 · 2HCl
分子量:
551.51
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
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产品名称

D-Val-Leu-Lys 对硝基苯胺 二盐酸盐, plasmin substrate

SMILES string

Cl.[N+](=O)([O-])c1ccc(cc1)NC(=O)C(NC(=O)C(NC(=O)C(N)C(C)C)CC(C)C)CCCCN

InChI

1S/C23H38N6O5.ClH/c1-14(2)13-19(28-23(32)20(25)15(3)4)22(31)27-18(7-5-6-12-24)21(30)26-16-8-10-17(11-9-16)29(33)34;/h8-11,14-15,18-20H,5-7,12-13,24-25H2,1-4H3,(H,26,30)(H,27,31)(H,28,32);1H

InChI key

ITWYYDDNWFVYSU-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear, light yellow

storage temp.

−20°C

Quality Level

Application

D-Val-Leu-Lys-对硝基苯胺二盐酸盐已用于:
  • 作为显色底物,测定纤溶酶原激活物活性
  • 作为对硝基苯胺(pNA)底物,测定中介蝮( Gloydius intermedius)蛇毒中的丝氨酸蛋白酶异构体活性
  • 作为牛奶/奶油样品总纤溶酶检测底物

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S Vijayakumar et al.
Journal of dairy science, 98(10), 6678-6691 (2015-08-04)
The shelf life of pasteurized milk is limited by heat-stable proteases, which cause gelation and bitter taste upon extended storage of milk. Ultra-high temperature processing inactivates proteases but detrimentally affects milk's sensory quality. An adjunct to pasteurization is desired to
Zhang-Min Yang et al.
Journal of proteomics, 164, 19-32 (2017-05-31)
Nine distinct venom serine proteases (vSPs) of Gloydius intermedius were studied by transcriptomic, sub-proteomic and phylogenetic analyses. Their complete amino acid sequences were deduced after Expression Sequence Tag (EST) analyses followed by cDNA cloning and sequencing. These vSPs appear to
Ezio Fasoli et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 930, 13-21 (2013-05-25)
Despite membrane-based separations offering superior alternative to packed bed chromatographic processes, there has been a substantial lacuna in their actual application to separation processes. One of the major reasons behind this is the lack of availability of appropriately modified or
Role of lysine binding regions in the kinetic properties of human plasmin.
J P Morris et al.
Biochemistry, 20(17), 4811-4816 (1981-08-18)
Warren B Nothnick et al.
PloS one, 9(6), e100336-e100336 (2014-06-18)
Endometriosis is defined as the growth of endometrial glandular and stromal components in ectopic locations and affects as many as 10% of all women of reproductive age. Despite its high prevalence, the pathogenesis of endometriosis remains poorly understood. MicroRNAs, small

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