产品名称
D-Val-Leu-Lys 对硝基苯胺 二盐酸盐, plasmin substrate
SMILES string
Cl.[N+](=O)([O-])c1ccc(cc1)NC(=O)C(NC(=O)C(NC(=O)C(N)C(C)C)CC(C)C)CCCCN
InChI
1S/C23H38N6O5.ClH/c1-14(2)13-19(28-23(32)20(25)15(3)4)22(31)27-18(7-5-6-12-24)21(30)26-16-8-10-17(11-9-16)29(33)34;/h8-11,14-15,18-20H,5-7,12-13,24-25H2,1-4H3,(H,26,30)(H,27,31)(H,28,32);1H
InChI key
ITWYYDDNWFVYSU-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
solubility
water: 50 mg/mL, clear, light yellow
storage temp.
−20°C
Quality Level
Application
D-Val-Leu-Lys-对硝基苯胺二盐酸盐已用于:
- 作为显色底物,测定纤溶酶原激活物活性
- 作为对硝基苯胺(pNA)底物,测定中介蝮( Gloydius intermedius)蛇毒中的丝氨酸蛋白酶异构体活性
- 作为牛奶/奶油样品总纤溶酶检测底物
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
S Vijayakumar et al.
Journal of dairy science, 98(10), 6678-6691 (2015-08-04)
The shelf life of pasteurized milk is limited by heat-stable proteases, which cause gelation and bitter taste upon extended storage of milk. Ultra-high temperature processing inactivates proteases but detrimentally affects milk's sensory quality. An adjunct to pasteurization is desired to
Zhang-Min Yang et al.
Journal of proteomics, 164, 19-32 (2017-05-31)
Nine distinct venom serine proteases (vSPs) of Gloydius intermedius were studied by transcriptomic, sub-proteomic and phylogenetic analyses. Their complete amino acid sequences were deduced after Expression Sequence Tag (EST) analyses followed by cDNA cloning and sequencing. These vSPs appear to
Ezio Fasoli et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 930, 13-21 (2013-05-25)
Despite membrane-based separations offering superior alternative to packed bed chromatographic processes, there has been a substantial lacuna in their actual application to separation processes. One of the major reasons behind this is the lack of availability of appropriately modified or
Role of lysine binding regions in the kinetic properties of human plasmin.
J P Morris et al.
Biochemistry, 20(17), 4811-4816 (1981-08-18)
Warren B Nothnick et al.
PloS one, 9(6), e100336-e100336 (2014-06-18)
Endometriosis is defined as the growth of endometrial glandular and stromal components in ectopic locations and affects as many as 10% of all women of reproductive age. Despite its high prevalence, the pathogenesis of endometriosis remains poorly understood. MicroRNAs, small
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