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V8379

Human Vitronectin

Name: Human Vitronectin
Brand: SIGMA

from human plasma, powder, suitable for cell culture

别名:

血清扩散因子

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关于此项目

化学文摘社编号:

83380-82-9

UNSPSC Code:

12352202

NACRES:

NA.75

MDL number:

MFCD00132575

Biological source:

human plasma

Form:

lyophilized powder

Technique(s):

cell culture | mammalian: suitable

Mol wt:

A subunit 75 kDa, B subunit 65 kDa

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产品名称

玻连蛋白来源于人类血浆, lyophilized powder, BioReagent, suitable for cell culture

biological source

human plasma

Quality Level

300

product line

BioReagent

form

lyophilized powder

mol wt

A subunit 75 kDa, B subunit 65 kDa

packaging

pkg of 50 μg

technique(s)

cell culture | mammalian: suitable

surface coverage

0.1 μg/cm²

solubility

water: soluble 0.050 mg/mL, clear, colorless

UniProt accession no.

P04004

shipped in

ambient

storage temp.

2-8°C

Gene Information

human ... VTN(7448)

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Application

玻连蛋白可用于具有整联蛋白受体（与玻连蛋白结合）的细胞，包括血小板、内皮细胞、黑素瘤细胞和骨肉瘤。推荐将其作为细胞培养基质成分，浓度为 0.1 μg/cm²。附着的最佳条件取决于细胞系和具体应用。

Biochem/physiol Actions

玻连蛋白结合糖胺聚糖，作为补体系统的细胞溶解攻击复合物的一种抑制剂，在凝血过程中与凝血酶和抗凝血酶 III 相互作用，并可能在凝血途径中发挥作用。

Preparation Note

该产品作为细胞培养物检测的冻干品（来自缓冲盐水）。由于玻连蛋白对亲水表面具有强亲和力，建议在操作过程中使用聚丙烯容器。每瓶产品可以重悬于 1mL 水中。然后应使用 0.2μm 膜对储备溶液进行过滤灭菌，等分并冷冻以便长期保存。

Other Notes

玻连蛋白是一种存在于血浆和组织中的糖蛋白，并且是血浆中与纤连蛋白结合的主要细胞粘附蛋白之一。玻连蛋白的 N-末端残基与生长调节素 B 相同，随后的序列是与特定细胞表面受体相互作用的 R-G-D 序列。玻连蛋白的中心结构域富含疏水残基。C 末端附近是富含精氨酸的区域，具有肝素结合活性。

Disclaimer

供研究使用在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

该冻干品应在 2-8℃ 下干燥储存。在这些条件下，它可以稳定至少 2 年。等分试样应储存在 -20°C 或 -70°C，但应避免反复冻融。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

高风险级别生物产品--人源产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000468922

0000200712

0000101588

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全球贸易项目编号

货号	GTIN
V8379-50UG	04061837481468

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