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经验公式(希尔记法):
C11H11Cl2N3O · HCl
化学文摘社编号:
分子量:
308.59
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
InChI key
YPNWSZJDAKOUAW-UHFFFAOYSA-N
SMILES string
Cl.Clc1cc2NC(=O)C3CNCCN3c2cc1Cl
InChI
1S/C11H11Cl2N3O.ClH/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8;/h3-4,10,14H,1-2,5H2,(H,15,17);1H
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to off-white
solubility
DMSO: >10 mg/mL
originator
Wyeth
storage temp.
room temp
Quality Level
Biochem/physiol Actions
The 5-HT2C receptors have been implicated in conditions including obesity, anxiety, depression, OCD, schizophrenia, migraine, nociception and erectile dysfunction.
Features and Benefits
This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
存储类别
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Adam L Halberstadt et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 34(8), 1958-1967 (2009-03-27)
Although it is well established that hallucinogens act as 5-HT(2A) and 5-HT(2C) receptor agonists, little is known about the relative contributions of 5-HT(2A) and 5-HT(2C) receptors to the acute behavioral effects of these drugs. The behavioral pattern monitor was used
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