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About This Item

经验公式(希尔记法):
C13H8BrNO3
CAS Number:
分子量:
306.11
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77
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质量水平

方案

≥98% (HPLC)

表单

solid

溶解性

DMSO: ≥20 mg/mL

创始人

Wyeth

储存温度

2-8°C

SMILES字符串

Oc1ccc(cc1)-c2nc3cc(O)cc(Br)c3o2

InChI

1S/C13H8BrNO3/c14-10-5-9(17)6-11-12(10)18-13(15-11)7-1-3-8(16)4-2-7/h1-6,16-17H

InChI key

BAAILVWEAXFTSF-UHFFFAOYSA-N

一般描述

WAY-200070 is a potent, selective estrogen receptor-beta (ER-β) agonist (IC50 2.3 nM vs. 155 nM for ER-α) with anxiolytic-like and antidepressant-like effects.

应用

WAY-200070, a selective estrogen receptor-beta (ER-β) agonist, may be used in estrogen receptor signaling research along with other ERβ agonists [diarylpropionitrile (DPN)] and antagonist to help identify and differentiate the functions of estrogen receptor-beta(s) (ER-β) involved in processes such as regulation of the physiology of the endocrine pancreas; modulation of visceral pain; and stress response. WAY-200070 may be used to help establish that an observed physiological or cell signaling response is ER-β-dependent, especially versus ERα.

生化/生理作用

Potent, selective estrogen receptor-beta (ER-β) agonist (IC50 2.3 nM vs 155 nM for ER-α) with anxiolytic-like and antidepressant-like effects.

特点和优势

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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